Psychotic Disorder Clinical Trials

57 recruitingLast updated: June 18, 2026

There are 57 actively recruiting psychotic disorder clinical trials across 26 countries. Studies span Not Applicable, Phase 1, Phase 2. Top locations include Paris, France, London, United Kingdom, Barcelona, Spain. Updated daily from ClinicalTrials.gov.


Psychotic Disorder Trials at a Glance

57 actively recruiting trials for psychotic disorder are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 42 trials, with the heaviest enrollment activity in Paris, London, and Barcelona. Lead sponsors running psychotic disorder studies include Charite University, Berlin, Germany, Bjorn H. Ebdrup, and Massachusetts General Hospital.

Browse psychotic disorder trials by phase

Treatments under study

About Psychotic Disorder Clinical Trials

Looking for clinical trials for Psychotic Disorder? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Psychotic Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Psychotic Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 57 trials

Recruiting
Not Applicable

Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

Depressive DisorderPsychotic DisordersAnxiety Disorders+1 more
Massachusetts General Hospital70 enrolled1 locationNCT05962879
Recruiting
Not Applicable

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Psychotic DisordersAnxiety DisordersMood Disorders
Parnassia Groep2,500 enrolled9 locationsNCT05656469
Recruiting

Semantic and Syntactic Computerized Analysis of Free Speech

Psychotic DisordersPsychosisSchizophrenia and Related Disorders+2 more
University Hospital, Brest215 enrolled3 locationsNCT03525054
Recruiting
Not Applicable

Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use

Cognitive DysfunctionPsychotic DisordersCannabis Use+5 more
Douglas Mental Health University Institute134 enrolled1 locationNCT05445180
Recruiting
Not Applicable

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Psychotic DisordersAnxiety DisordersMood Disorders
Massachusetts General Hospital192 enrolled1 locationNCT06929442
Recruiting

Validation and Impact of Cardiorespiratory Fitness in Severe Mental Illness - the Heart in Mind Project

Bipolar Affective DisorderSevere Mental IllnessSchizophrenia Spectrum & Other Psychotic Disorders
Bjorn H. Ebdrup75 enrolled1 locationNCT06743711
Recruiting
Not Applicable

REFLECT: A Novel Group-Based Compassion-Focussed Cognitive Behavioural Approach to Core Beliefs in Psychosis

Schizophrenia Spectrum & Other Psychotic Disorders
University of Toronto38 enrolled1 locationNCT07569471
Recruiting
Not Applicable

Racial Disparities in the Expression of Paranoia

Psychotic DisordersParanoia
Indiana University480 enrolled1 locationNCT07460453
Recruiting
Not Applicable

Multimodal Physical Exercise Program (Physical Exercise for Psychosis) for People With Psychosis Treated With Long-Acting Injectable Antipsychotics

Psychotic DisordersSevere Mental IllnessSchizophrenia Spectrum Disorders (SSD)
University of Trás-os-Montes and Alto Douro44 enrolled1 locationNCT07360665
Recruiting
Not Applicable

Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis

SchizophreniaPsychotic DisordersSchizo Affective Disorder
The Royal Ottawa Mental Health Centre52 enrolled1 locationNCT05973110
Recruiting
Not Applicable

Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders

PSP - Progressive Supranuclear PalsyAlzheimer Dementia (AD)MSA - Multiple System Atrophy+7 more
Universitaire Ziekenhuizen KU Leuven300 enrolled1 locationNCT07509125
Recruiting
Not Applicable

Study of Self-Recognition and Self/Other Distinction Disorders in Patients With Psychological Vulnerability

Psychotic DisorderPsychosis of Childhood Borderline
University Hospital, Brest34 enrolled1 locationNCT04945278
Recruiting

Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population

Eating DisordersPsychotic DisorderMood Disorders in Children and Adolescents+1 more
Meyer Children's Hospital IRCCS100 enrolled6 locationsNCT06870006
Recruiting
Not Applicable

Feasibility, Acceptability, and Preliminary Efficacy of Yoga-based Group Intervention for Outpatients With Schizophrenia Spectrum Disorders

Schizophrenia Spectrum DisordersPsychotic Disorders
Charite University, Berlin, Germany60 enrolled1 locationNCT07455929
Recruiting

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

SchizophreniaSchizoaffective DisorderDelusional Disorder+4 more
Beth Israel Deaconess Medical Center320 enrolled6 locationsNCT06740383
Recruiting
Not Applicable

Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders

SchizophreniaSchizophrenia Spectrum DisordersPsychotic Disorders+3 more
Charite University, Berlin, Germany60 enrolled1 locationNCT07395206
Recruiting
Not Applicable

Brain Stimulation to the Hippocampus in Schizophrenia

Schizophrenia DisordersMental DisorderPsychotic Disorder
Stanford University60 enrolled1 locationNCT07010614
Recruiting
Not Applicable

Evaluation of a Brief Intervention to Improve Engagement in Early Intervention Services for Psychosis

Psychotic DisordersEngagement, PatientPsychiatric Hospitalization
Nova Scotia Health Authority40 enrolled1 locationNCT06410508
Recruiting
Not Applicable

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

DepressionSerious Mental IllnessPsychotic Disorder+1 more
Massachusetts General Hospital40 enrolled1 locationNCT07359157
Recruiting
Not Applicable

CBT-CP for Veterans With SMI

Chronic PainSchizophreniaPsychotic Disorders+2 more
VA Office of Research and Development190 enrolled1 locationNCT06758414