Mood Disorder Clinical Trials

6 recruiting

Mood Disorder Trials at a Glance

45 actively recruiting trials for mood disorder are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Bethesda, Toronto, and Halifax. Lead sponsors running mood disorder studies include National Institute of Mental Health (NIMH), Massachusetts General Hospital, and IRCCS San Raffaele.

Browse mood disorder trials by phase

Treatments under study

About Mood Disorder Clinical Trials

Looking for clinical trials for Mood Disorder? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mood Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mood Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting

Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

Anxiety DisordersMood Disorders
National Institute of Mental Health (NIMH)390 enrolled1 locationNCT00397111
Recruiting

Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

Mood Disorder
National Institute of Mental Health (NIMH)2,350 enrolled1 locationNCT00025935
Recruiting
Not Applicable

Efficacy of Remote Monitoring in Patients Treated for Moderate to Severe Major Depressive Episodes

Mood Disorder (Depressive Episodes)
Resilience594 enrolled6 locationsNCT07087353
Recruiting

Investigation on Suicide Risk Factors of Patients With Mood Disorders

SuicideMood Disorders
Tianjin Anding Hospital300 enrolled1 locationNCT07523490
Recruiting
Not Applicable

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Insulin ResistanceHyperinsulinismDepression+5 more
Colorado State University300 enrolled2 locationsNCT05543083
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Psychotic DisordersAnxiety DisordersMood Disorders
Massachusetts General Hospital192 enrolled1 locationNCT06929442
Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting

Study of Premenstrual Syndrome and Premenstrual Dysphoria

Mood Disorder
National Institute of Mental Health (NIMH)1,600 enrolled1 locationNCT00001177
Recruiting
Not Applicable

Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery

Anxiety in PregnancyMood Disorder Due to Specified Medical Condition
University of Colorado, Denver80 enrolled1 locationNCT06949813
Recruiting

Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population

Eating DisordersPsychotic DisorderMood Disorders in Children and Adolescents+1 more
Meyer Children's Hospital IRCCS100 enrolled6 locationsNCT06870006
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

Anxiety Disorder GeneralizedADHDDepression Disorders+2 more
Gaize50 enrolled1 locationNCT07389473
Recruiting
Not Applicable

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Psychotic DisordersAnxiety DisordersMood Disorders
Maastricht University Medical Center2,500 enrolled9 locationsNCT05656469
Recruiting
Not Applicable

Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression

Depression - Major Depressive DisorderMood DisordersLate Life Depression (LLD)+1 more
Centre for Addiction and Mental Health280 enrolled2 locationsNCT06854367
Recruiting

An Innovative Master Platform for Clinical Trials in Mood Disorders

Depressive DisorderMood DisordersBipolar and Related Disorders
St. Joseph's Healthcare Hamilton900 enrolled9 locationsNCT06408012
Recruiting
Not Applicable

Imagery Rescripting in Primary Care

Mood DisordersMajor Depressive DiorderLow Self-Esteem
University of Amsterdam12 enrolled1 locationNCT07362511
Recruiting
Not Applicable

Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT

Depression - Major Depressive DisorderOlder Adults (65 Years and Older)Mood Disorders+3 more
KU Leuven82 enrolled1 locationNCT07211750
Recruiting
Not Applicable

Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study

DepressionBipolar Affective DisorderSchizophenia Disorder+1 more
Peking University325 enrolled1 locationNCT06831435