Phase 4 Sedation Clinical Trials
23 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 23 trials
Recruiting
Phase 4
A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy
Colonic PolypSedation Complication
Clinical Hospital Centre Zagreb90 enrolled1 locationNCT07456111
Recruiting
Phase 4
Effect of IV Lidocaine on Duodenal Peristalsis and Sedation in ERCP
SedationERCPDuodenal Spasm
Ankara City Hospital Bilkent120 enrolled1 locationNCT07333859
Recruiting
Phase 4
Inhaled Sedation in Critically Ill Patients
SedationAirway Extubation
Instituto de Investigación Hospital Universitario La Paz620 enrolled22 locationsNCT07000526
Recruiting
Phase 4
Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients
SurgeryMechanical Ventilation ComplicationCritical Illness+3 more
Beijing Shijitan Hospital, Capital Medical University306 enrolled1 locationNCT06575530
Recruiting
Phase 4
Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia
EsketamineDexmedetomidinePreoperative Anxiety+5 more
Second Affiliated Hospital of Wenzhou Medical University80 enrolled2 locationsNCT06853431
Recruiting
Phase 4
Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
SedationEmergence Delirium
Assiut University60 enrolled1 locationNCT05821972
Recruiting
Phase 4
Oral vs IV Sedation for Cataract Surgery in Older Adults
Older AdultsSedationPerioperative Care+2 more
University of California, San Francisco20 enrolled1 locationNCT07154147
Recruiting
Phase 4
Comparison of Safety and Efficacy for Different Sedation Regimens During Colonoscopy
Conscious SedationColonoscopyDeep Sedations
Qassim Health Cluster157 enrolled1 locationNCT06763705
Recruiting
Phase 4
Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial
Sedation for Diagnostic Gastroscopy
Koen Munters148 enrolled3 locationsNCT06614036
Recruiting
Phase 4
The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
Procedural SedationGIT Endoscopy
Theodor Bilharz Research Institute52 enrolled1 locationNCT06414395
Not Yet Recruiting
Phase 4
Continuous infusion of remimazolam for intraoperative sedation as a safe and effective option: a prospective clinical study.
Procedural or intraoperative sedation.
Antonia Kustura, MD50 enrolled1 locationACTRN12623000133639
Not Yet Recruiting
Phase 4
Sneezing under intravenous sedation during nasal local anaesthetic injection for plastic surgery procedures
SneezingIntravenous sedation
Department of Anaesthesia, Portland District Health60 enrolled1 locationACTRN12621000850875
Recruiting
Phase 4
The effect of early sedation with dexmedetomidine compared with placebo on 90-day mortality in older critically ill patients
Mechanical VentilationSedation
Monash University3,500 enrolled19 locationsACTRN12620001088932
Recruiting
Phase 4
One-Needle Approach to Paediatric Procedural Sedation using Ketamine: A Randomised Control Trial.
Procedural Sedation
Gold Coast Hospital and Health Service537 enrolled2 locationsACTRN12619000612112
Completed
Phase 4
Effect of adding ketamine infusion to propofol sedation on hemodynamic changes and recovery in patients undergoing elective lower limb surgery under spinal anaesthesia
sedation for elective lower limb surgery
Aysu Hayriye Tezcan61 enrolled1 locationACTRN12615000372583
Recruiting
Phase 4
A comparison of dexmedetomidine combined with propofol for conscious sedation during endoscopic retrograde cholangiopancreatography(ERCP)
Although target controlled infusion(TCI) systems decrease the risk of respiratory during sedation with propofol, the risk persists.
Dr Qianbo Chen60 enrolledACTRN12612000964819
Recruiting
Phase 4
A comparison of propofol and dexmedetomidine for sedation during hip and knee arthoplasty.
Sedation during hip and knee arthroplasty, which is often associated with a need for airway support due to respiratory depression and reduced airway tone.
Dr Mark Suss40 enrolled1 locationACTRN12612000211864
Completed
Phase 4
Using ketamine (an anesthetic agent) with Propofol (a hypnotic agent commonly used during sedation) during visual examination of large intestine reduces propofol dosage improves the quality of sedation
Patients undergoing colonoscopy under sedation
Prof. Mehmet Ayhan KUZU100 enrolled1 locationACTRN12612000162819
Completed
Phase 4
The effects of applying perianal local anesthetics on patient comfort during visual examination of the last part of large intestine
Patients undergoing sigmoidoscopy without any sedation
Prof. Mehmet Ayhan KUZU175 enrolled1 locationACTRN12611000715976
Not Yet Recruiting
Phase 4
Recovery of driving ability after propofol-only sedation
Driving ability after propofol only sedation for endoscopy
Department of Anaesthesia - Monash Medical Centre100 enrolled1 locationACTRN12611000634976