Phase 1 Surgery Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
Topical Infliximab in Eyes With Penetrating Keratoplasty
Glaucoma Following Surgery
Centre hospitalier de l'Université de Montréal (CHUM)50 enrolled1 locationNCT05180994
Recruiting
Phase 1Phase 2
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 1
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
ObesitySmoking CessationBariatric Surgery Patients
Yale University20 enrolled1 locationNCT07224087
Recruiting
Phase 1
Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer
Prostate Cancer SurgeryProstate Cancer (Adenocarcinoma)Prostate CA
AdventHealth30 enrolled1 locationNCT06631521
Recruiting
Phase 1
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
ObesityBariatric SurgeryAdolescent Obesity+3 more
University of Colorado, Denver40 enrolled1 locationNCT06575738
Recruiting
Phase 1Phase 2
Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
Enhanced Recovery After Surgery in a Pediatric Population
University of Chicago100 enrolled1 locationNCT06538584
Recruiting
Phase 1Phase 2
Double-blind Pilot Study on the Effect of Anionic Exposome Enrichment (Biow) on Recovery and Sleep Quality in Postoperative Patients
Postoperative RecoveryInflammatory Response After Surgery
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz150 enrolled1 locationNCT06968000
Recruiting
Phase 1
Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds
Wound HealingMohs Micrographic Surgery
Icahn School of Medicine at Mount Sinai102 enrolled1 locationNCT06941467
Recruiting
Phase 1
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
SurgeryPostoperative Blood Loss
Vanderbilt University Medical Center60 enrolled1 locationNCT05774717
Recruiting
Phase 1Phase 2
Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant
Hepatocellular Carcinoma (HCC)Liver Transplant SurgeryMacrovascular Invasion+1 more
University Health Network, Toronto48 enrolled2 locationsNCT06725121
Completed
Phase 1
A pilot randomised open-label taste-testing study to evaluate the acceptability of chocolate-based tramadol in children
Pain management in relation to surgery
Princess Margaret Hospital150 enrolled2 locationsACTRN12617001490369
Completed
Phase 1
A Phase 1 Study of a Novel Bi-Directional Arterial Cannula in Patients requiring Peripheral Cannulation for Cardiac Surgery.
Patients who require peripheral cannulation for cardiac surgery.
Alfred Hospital15 enrolled1 locationACTRN12615001008516