Phase 2 Surgery Clinical Trials

77 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 77 trials

Recruiting
Phase 2

A Study of LY4515100 in Participants With Pain Following Third Molar Removal

Acute PainMolar, ThirdMolar+1 more
Eli Lilly and Company212 enrolled1 locationNCT07511816
Recruiting
Phase 2

Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC)

Aortic SurgeryExtracorporeal Circulation
Nantes University Hospital25 enrolled1 locationNCT07267013
Recruiting
Phase 1Phase 2

Topical Infliximab in Eyes With Penetrating Keratoplasty

Glaucoma Following Surgery
Centre hospitalier de l'Université de Montréal (CHUM)50 enrolled1 locationNCT05180994
Recruiting
Phase 2Phase 3

Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management

Open Colorectal SurgeryAppendectomyPostoperative Pain+5 more
Dr. Asma Abdus Salam263 enrolled1 locationNCT06996561
Recruiting
Phase 2

Efficacy and Safety Evaluation of Absorbable and Moldable Skull Base Support Plates in Extended Endoscopic Endonasal Transsphenoidal Surgery: A Prospective, Randomized, Controlled Study

Endonasal SurgerySellar TumorCsf Leakage
Nanfang Hospital, Southern Medical University126 enrolled8 locationsNCT07539792
Recruiting
Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 1Phase 2

Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children

Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 2

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine MetastasesSpine Stereotactic Radiosurgery (sSRS)
Case Comprehensive Cancer Center130 enrolled1 locationNCT04218617
Recruiting
Phase 2

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

SurgeryCardiac DiseaseBleeding
Northwell Health140 enrolled1 locationNCT07032792
Recruiting
Phase 2

Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection

Prostate Cancer SurgeryProstate Cancer Metastatic Disease
Clinton Bahler22 enrolled3 locationsNCT06849544
Recruiting
Phase 2Phase 3

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 2Phase 3

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

Injury of Ureter During Surgery (Disorder)
Curadel Surgical Innovations, Inc.336 enrolled10 locationsNCT06101745
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting
Phase 2

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal NeoplasmsRobotic Surgery and/or RadiotherapyLymphoscintigraphy
M.D. Anderson Cancer Center240 enrolled1 locationNCT06167291
Recruiting
Phase 2

Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery

Cardiac SurgeryChronic Iron Deficiency Anaemia
University Health Network, Toronto60 enrolled3 locationsNCT06287619
Recruiting
Phase 2

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Acute Kidney InjuryCardiac Surgery
Arch Biopartners Inc.240 enrolled9 locationsNCT05879432
Recruiting
Phase 2

Efficacy of Adapted Physical Activity on a Walking Platform in Elderly Patients HOspitalized for Cancer Surgery

SurgeryOncologyElderly Patients
Centre Francois Baclesse60 enrolled2 locationsNCT06201884
Recruiting
Phase 2Phase 3

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Lung Cancer (NSCLC)AnalgeticVideo Assisted Thoracic Surgery (VATS)+1 more
Rigshospitalet, Denmark80 enrolled1 locationNCT07213375
Recruiting
Phase 2

A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block

AnalgesiaPain, AcuteNerve Block+1 more
McGill University Health Centre/Research Institute of the McGill University Health Centre69 enrolled1 locationNCT07249827
Recruiting
Phase 2

Delayed Cold-Stored Platelets -PLTS-1

BleedingCardiac SurgeryCardiopulmonary Bypass+1 more
University Health Network, Toronto150 enrolled2 locationsNCT06147531