Phase 3 Surgery Clinical Trials

86 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 86 trials

Recruiting
Phase 3

Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries

Sphenopalatine BlockTurbinate Surgery
Ain Shams University50 enrolled1 locationNCT07299630
Recruiting
Phase 3

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Phase 3

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Complex Cardiovascular Surgery With Cardiopulmonary Bypass
CSL Behring200 enrolled19 locationsNCT07094087
Recruiting
Phase 2Phase 3

Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management

Open Colorectal SurgeryAppendectomyPostoperative Pain+5 more
Dr. Asma Abdus Salam263 enrolled1 locationNCT06996561
Recruiting
Phase 3

Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery

Bariatric SurgeryCardiac Surgery With Sternotomy
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07539623
Recruiting
Phase 3

A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China.

Pain After Abdominal Surgery
The Third Xiangya Hospital of Central South University333 enrolled2 locationsNCT07353307
Recruiting
Phase 3

Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial

Breast CancerMastectomyBreast Cancer Female+1 more
Monash University4,300 enrolled47 locationsNCT05072314
Recruiting
Phase 3

Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers

Radiotherapy, AdjuvantOral Cavity CarcinomaFlap+1 more
Centre Francois Baclesse348 enrolled25 locationsNCT06798922
Recruiting
Phase 2Phase 3

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 2Phase 3

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

Injury of Ureter During Surgery (Disorder)
Curadel Surgical Innovations, Inc.336 enrolled10 locationsNCT06101745
Recruiting
Phase 3

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 3

Evaluation of Analgesia for Cardiac Elective Surgery in Children

Pediatric Cardiac Surgery
Senthil Sadhasivam500 enrolled1 locationNCT06626035
Recruiting
Phase 3

Sentinel Node Biopsy in Endometrial Cancer

SurgerySentinel Lymph NodeEndometrial Cancer Stage I
Queensland Centre for Gynaecological Cancer760 enrolled19 locationsNCT04073706
Recruiting
Phase 3

Neoadjuvant Treatment Modalities in Esophageal Cancer

Esophageal CancerSurgeryChemotherapy Effect+4 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled1 locationNCT04821843
Recruiting
Phase 2Phase 3

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Lung Cancer (NSCLC)AnalgeticVideo Assisted Thoracic Surgery (VATS)+1 more
Rigshospitalet, Denmark80 enrolled1 locationNCT07213375
Recruiting
Phase 3

Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution

ENT DisorderNasal ProceduresNasal Anesthesia+1 more
Noden Pharma40 enrolled4 locationsNCT04792034
Recruiting
Phase 3

Huaxi Tunnel Technique For Recurrent Laryngeal Nerve Exposure And Dissection In Thyroid Surgery

Patients Undergoing Open Thyroid Surgery
West China Hospital700 enrolled1 locationNCT07298616
Recruiting
Phase 3

Desflurane vs. Propofol for Cardiac Anesthesia

Coronary Artery Bypass GraftingCardiac Surgery
Xijing Hospital3,560 enrolled14 locationsNCT07116733
Recruiting
Phase 3

Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL)

Burns Surgery
Assistance Publique - Hôpitaux de Paris506 enrolled1 locationNCT04292054
Recruiting
Phase 3

The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery

Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
Jiangsu HengRui Medicine Co., Ltd.101 enrolled1 locationNCT06507436