Phase 3 Surgery Clinical Trials
97 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 97 trials
Recruiting
Phase 3
Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
Sphenopalatine BlockTurbinate Surgery
Ain Shams University50 enrolled1 locationNCT07299630
Recruiting
Phase 3
Hydrocortisone Plus Fludrocortisone in High-risk Patients Undergoing for Cardiac Surgery
Inflammation in Cardiac Surgery
Centre Hospitalier Universitaire, Amiens196 enrolled1 locationNCT07037043
Recruiting
Phase 3
Suzetrigine in Total Hip Arthroplasty
Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting
Phase 3
Levetiracetam for Seizure Prevention After Brain Tumor Surgery
Postoperative Seizures After Brain Tumor Surgery
Beijing Tiantan Hospital558 enrolled1 locationNCT07239115
Recruiting
Phase 3
Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
Cardiac SurgeryCardiopulmonary BypassNitric Oxide+1 more
Xijing Hospital3,650 enrolled3 locationsNCT06702553
Recruiting
Phase 3
Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 3
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Phase 3
Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery
Post Operative PainBariatric SurgeryCardiac Surgery With Sternotomy
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07539623
Recruiting
Phase 3
Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)
Complex Cardiovascular Surgery With Cardiopulmonary Bypass
CSL Behring200 enrolled18 locationsNCT07094087
Recruiting
Phase 3
Evaluation of Analgesia for Cardiac Elective Surgery in Children
Pediatric Cardiac Surgery
Senthil Sadhasivam500 enrolled1 locationNCT06626035
Recruiting
Phase 3
Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
Quality of Life (QOL)Rectal CancerLARS - Low Anterior Resection Syndrome+1 more
University Hospital, Basel, Switzerland140 enrolled5 locationsNCT06936774
Recruiting
Phase 3
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
DeliriumSurgery--Complications
Washington University School of Medicine46 enrolled1 locationNCT06969287
Recruiting
Phase 3
Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN
Total knee replacement surgeryPost Operative Pain
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07548385
Recruiting
Phase 2Phase 3
Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management
Open Colorectal SurgeryAppendectomyPostoperative Pain+5 more
Dr. Asma Abdus Salam263 enrolled1 locationNCT06996561
Recruiting
Phase 3
A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China.
Pain After Abdominal Surgery
The Third Xiangya Hospital of Central South University333 enrolled2 locationsNCT07353307
Recruiting
Phase 3
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
Breast CancerMastectomyBreast Cancer Female+1 more
Monash University4,300 enrolled47 locationsNCT05072314
Recruiting
Phase 3
Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers
Radiotherapy, AdjuvantOral Cavity CarcinomaFlap+1 more
Centre Francois Baclesse348 enrolled25 locationsNCT06798922
Recruiting
Phase 2Phase 3
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 2Phase 3
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
Injury of Ureter During Surgery (Disorder)
Curadel Surgical Innovations, Inc.336 enrolled10 locationsNCT06101745
Recruiting
Phase 3
Sentinel Node Biopsy in Endometrial Cancer
SurgerySentinel Lymph NodeEndometrial Cancer Stage I
Queensland Centre for Gynaecological Cancer760 enrolled19 locationsNCT04073706