Phase 4 Surgery Clinical Trials

167 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 167 trials

Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction

OphthalmologyCataract Surgery AnesthesiaOral Anxiolytic+1 more
National Taiwan University Hospital250 enrolled1 locationNCT06874452
Recruiting
Phase 4

Anesthesia and Non-small Cell Lung Cancer Recurrence

SurgeryNon-small Cell Lung CancerAnesthesia
Samsung Medical Center5,384 enrolled1 locationNCT06330038
Recruiting
Phase 4

PeRiOperative Medicine Platform Trial

Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

SurgeryPain, Postoperative
University of Michigan900 enrolled8 locationsNCT05722002
Recruiting
Phase 4

Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

SurgeryEsketamineDexmedetomidine+1 more
Peking University First Hospital316 enrolled1 locationNCT07308756
Recruiting
Phase 4

Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intubation on an Outpatient Basis

Laparoscopic Cholecystectomy Surgery
University Hospital, Limoges120 enrolled2 locationsNCT07019818
Recruiting
Phase 4

Sore Throat After Open Neck Elective Surgery

Postoperative Sore Throat, Cough, HoarsenessThyroid and Parathyroid Surgery
Saint Petersburg State University, Russia764 enrolled1 locationNCT07124650
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Postoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106
Recruiting
Phase 4

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

Pain, PostoperativeAnkle Fracture Surgery
Jenna-Leigh Wilson100 enrolled1 locationNCT06949826
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+1 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4

Effect of Intraoperative Morphine on Postoperative Pain After CABG

Postoperative PainPain After SurgeryCardiac Surgery Patient
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07472959
Recruiting
Phase 4

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

AnesthesiaSurgery With General Anesthesia
University of California, San Francisco18,000 enrolled8 locationsNCT06802224
Recruiting
Phase 4

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

Complex Obstetric Surgery
University of Tennessee120 enrolled1 locationNCT06925152
Recruiting
Phase 4

Comparison Between Standard and Reduced Doses of Indocyanine Green in Fluorescence Cholangiography During Laparoscopic Cholecystectomy.

Laparoscopic Cholecystectomy Surgery
Instituto de Investigación Biomédica de Salamanca122 enrolled2 locationsNCT07195331
Recruiting
Phase 4

Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery

Lung Resection SurgeryAnesthesia General
Francisco Andres de la Gala177 enrolled1 locationNCT07461779
Recruiting
Phase 4

Intrapleural Ropivacaine Infusion in Cardiac Surgery

Coronary Artery DiseaseCardiac SurgeryValvular Diseases
Saint Petersburg State University, Russia116 enrolled2 locationsNCT07116343
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

SurgeryPain, Post Operative
University of Michigan900 enrolled4 locationsNCT06671002
Recruiting
Phase 4

Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration

Laparoscopic Cholecystectomy SurgeryAnalgeisaLocal Anesthetic Infiltration
Rawalpindi Medical College100 enrolled1 locationNCT07409688
Recruiting
Phase 4

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal Junctional KyphosisAdult Spinal Deformity SurgeryThoracolumbosacral Orthosis
Hospital for Special Surgery, New York84 enrolled6 locationsNCT06491030