Phase 2 Trauma Clinical Trials

104 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 104 trials

Recruiting
Phase 2

Mindfulness-based Psilocybin Therapy for PTSD

Depression - Major Depressive DisorderPost Traumatic Stress Disorder
Anthony P King30 enrolled1 locationNCT07104916
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research800 enrolled9 locationsNCT05422612
Recruiting
Phase 2

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

TraumaHemorrhage
Jason Sperry1,050 enrolled15 locationsNCT05958342
Recruiting
Phase 2Phase 3

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

Post Traumatic Stress DisorderAlcohol Use Disorder
VA Office of Research and Development80 enrolled2 locationsNCT07118839
Recruiting
Phase 2

SPI-1005 in Adults Receiving Cochlear Implant

Hearing LossCochlear Trauma
Sound Pharmaceuticals, Incorporated40 enrolled6 locationsNCT06340633
Recruiting
Phase 2

Feasibility and Safety of Targeting Neutral vs Liberal Fluid Balance in Traumatic Brain Injured Patients- LIMIT-TBI Trial

Acute brain injuryTraumatic Brain InjuryNeurocritical Care+1 more
Erasme University Hospital88 enrolled3 locationsNCT07625995
Recruiting
Phase 2

Hyperbaric Oxygen Brain Injury Treatment Trial

Traumatic Brain Injury
Gaylan Rockswold200 enrolled11 locationsNCT02407028
Recruiting
Phase 2Phase 3

Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)

Metabolic SyndromeSpinal Cord InjuryTraumatic Spinal Cord Injury+1 more
Northwell Health60 enrolled3 locationsNCT07625332
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research200 enrolled9 locationsNCT05948540
Recruiting
Phase 2

MDMA-Assisted Massed Exposure Therapy for PTSD

Post Traumatic Stress Disorder
Emory University200 enrolled1 locationNCT07288151
Recruiting
Phase 2

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

Stress Disorders, Post-Traumatic
Emory University134 enrolled1 locationNCT02560805
Recruiting
Phase 2

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Post Traumatic Stress DisorderPTSD
Sunstone Medical70 enrolled1 locationNCT06902974
Recruiting
Phase 2

Human Upper Extremity Allotransplantation

Hand injuriesWounds and InjuriesAmputation, Traumatic
Johns Hopkins University30 enrolled1 locationNCT01459107
Recruiting
Phase 2

Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)

NeuroinflammationTraumatic Brain Injury (TBI) Patients
Lagos State University240 enrolled1 locationNCT07269457
Recruiting
Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Depressive DisorderPost Traumatic Stress DisorderSuicidal Ideation+2 more
Yale University30 enrolled1 locationNCT05786066
Recruiting
Phase 2

Dopaminergic Disruption Induced by Traumatic Coma: Dopaminergic Pathways Abnormalities and Biomarkers of Recovery Using MRI and 18F-LBT-999 PET

Coma, Traumatic
Institut National de la Santé Et de la Recherche Médicale, France55 enrolled1 locationNCT06930261
Recruiting
Phase 2

Personalized Nutrition to Improve Recovery in Trauma

Abdominal Trauma
Duke University150 enrolled1 locationNCT06065202
Recruiting
Phase 2

Treating Spinal Cord Injury With Early Normobaric Hyperoxia

Traumatic Spinal Cord Injuries
University of Florida12 enrolled1 locationNCT07465302
Recruiting
Phase 2

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277