Phase 4 Trauma Clinical Trials

33 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 33 trials

Recruiting
Phase 4

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

Traumatic Brain Injury
Wake Forest University Health Sciences600 enrolled1 locationNCT06866691
Recruiting
Phase 4

Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures

Soft Tissue DefectsSoft Tissue WoundsTraumatic Soft Tissue Defect
Aroa Biosurgery Limited30 enrolled2 locationsNCT07385313
Recruiting
Phase 4

Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures

Opioid UseFractures, BoneTrauma
Henry Ford Health System75 enrolled1 locationNCT06113211
Recruiting
Phase 4

Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization

Amputation; Traumatic, Hand
Centre hospitalier de l'Université de Montréal (CHUM)188 enrolled1 locationNCT04725201
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+1 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4

Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial

PolytraumaResuscitation, Trauma Patients
Pakistan Institute of Medical Sciences60 enrolled1 locationNCT07480655
Recruiting
Phase 4

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

Posttraumatic Stress Disorder (PTSD)
VA Office of Research and Development70 enrolled3 locationsNCT05776056
Recruiting
Phase 4

Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder

Post Traumatic Stress Disorder
NYU Langone Health80 enrolled1 locationNCT05391971
Recruiting
Phase 4

CEUS for Blunt Abdominal Trauma in Children

Trauma Abdomen
Children's Hospital of Philadelphia146 enrolled2 locationsNCT03490929
Recruiting
Phase 4

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

TraumaAcute Pain
University of California, Davis156 enrolled1 locationNCT04166877
Recruiting
Phase 4

Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction

Anterior Cruciate Ligament InjuriesACL InjuryPost-Traumatic Osteoarthritis of Knee+1 more
Hospital for Special Surgery, New York40 enrolled2 locationsNCT06311513
Recruiting
Phase 4

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Traumatic Brain InjuryBrain Tumor AdultWound Closure+3 more
University of Michigan160 enrolled1 locationNCT07225101
Recruiting
Phase 4

Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)

Traumatic Brain InjuriesSeizuresTraumatic Brain Injury (TBI) Patients
All India Institute of Medical Sciences, Jodhpur1,260 enrolled3 locationsNCT07072624
Recruiting
Phase 4

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

Sleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic
VA Office of Research and Development190 enrolled4 locationsNCT03642028
Recruiting
Phase 4

Computational Assessment of GABA Receptor Modulation in PTSD

Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Phase 4

Tranexamic Acid in Patients With Traumatic Bleeding Based on Dynamic Monitoring of Thromboelastography

Trauma Coagulopathy
Nanfang Hospital, Southern Medical University580 enrolled1 locationNCT06736860
Not Yet Recruiting
Phase 4

Rapid eye movement sleep & extinction trial in post-traumatic stress disorder

TraumaPTSD
the University of Melbourne80 enrolled1 locationACTRN12624001404516
Recruiting
Phase 4

Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS)

Non-Traumatic Subarachnoid Hemorrhage
Madeleine Puissant20 enrolled1 locationNCT06569212
Recruiting
Phase 4

Ketamine in Acute Brain Injury Patients.

Brain Injuries, Traumatic
Geert Meyfroidt, MD, PhD100 enrolled8 locationsNCT05097261
Recruiting
Phase 4

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Traumatic Brain InjuryIntracerebral HemorrhageSubarachnoid Hemorrhage, Aneurysmal
Rigshospitalet, Denmark400 enrolled1 locationNCT05095857