Phase 4 Trauma Clinical Trials
36 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 36 trials
Recruiting
Phase 4
Computational Assessment of GABA Receptor Modulation in PTSD
Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Phase 4
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
Orthopaedic traumaChronic Opioid Use
Massachusetts General Hospital458 enrolled2 locationsNCT06201676
Recruiting
Phase 4
Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery
Stress Disorders, Post-Traumatic
Massachusetts General Hospital80 enrolled1 locationNCT05853627
Recruiting
Phase 4
Buspirone and Melatonin for Depression Following Traumatic Brain Injury
DepressionBrain Injuries, Traumatic
Massachusetts General Hospital10 enrolled2 locationsNCT04400266
Recruiting
Phase 4
Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide
Traumatic Brain Injury
Wake Forest University Health Sciences600 enrolled1 locationNCT06866691
Recruiting
Phase 4
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Soft Tissue DefectsSoft Tissue WoundsTraumatic Soft Tissue Defect
Aroa Biosurgery Limited30 enrolled2 locationsNCT07385313
Recruiting
Phase 4
Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
Opioid UseFractures, BoneTrauma
Henry Ford Health System75 enrolled1 locationNCT06113211
Recruiting
Phase 4
Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization
Amputation; Traumatic, Hand
Centre hospitalier de l'Université de Montréal (CHUM)188 enrolled1 locationNCT04725201
Recruiting
Phase 4
Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults
Orthopaedic traumaLower Extremity FractureSurgical Fracture Repair+1 more
University of Maryland, Baltimore34 enrolled1 locationNCT07217626
Recruiting
Phase 4
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4
Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial
PolytraumaResuscitation, Trauma Patients
Pakistan Institute of Medical Sciences60 enrolled1 locationNCT07480655
Recruiting
Phase 4
Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints
Posttraumatic Stress Disorder (PTSD)
VA Office of Research and Development70 enrolled3 locationsNCT05776056
Recruiting
Phase 4
Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder
Post Traumatic Stress Disorder
NYU Langone Health80 enrolled1 locationNCT05391971
Recruiting
Phase 4
CEUS for Blunt Abdominal Trauma in Children
Trauma Abdomen
Children's Hospital of Philadelphia146 enrolled2 locationsNCT03490929
Recruiting
Phase 4
Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
TraumaAcute Pain
University of California, Davis156 enrolled1 locationNCT04166877
Recruiting
Phase 4
Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Anterior Cruciate Ligament InjuriesACL InjuryPost-Traumatic Osteoarthritis of Knee+1 more
Hospital for Special Surgery, New York40 enrolled2 locationsNCT06311513
Recruiting
Phase 4
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
Traumatic Brain InjuryBrain Tumor AdultWound Closure+3 more
University of Michigan160 enrolled1 locationNCT07225101
Recruiting
Phase 4
Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)
Traumatic Brain InjuriesSeizuresTraumatic Brain Injury (TBI) Patients
All India Institute of Medical Sciences, Jodhpur1,260 enrolled3 locationsNCT07072624
Recruiting
Phase 4
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Sleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic
VA Office of Research and Development190 enrolled4 locationsNCT03642028
Recruiting
Phase 4
Tranexamic Acid in Patients With Traumatic Bleeding Based on Dynamic Monitoring of Thromboelastography
Trauma Coagulopathy
Nanfang Hospital, Southern Medical University580 enrolled1 locationNCT06736860