Phase 1 Trauma Clinical Trials
31 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 31 trials
Recruiting
Phase 1
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Post Traumatic Stress DisorderDepressive Disorder, Major
Yale University50 enrolled1 locationNCT05915013
Recruiting
Phase 1
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
Surgical wound infectionTraumatic Wound Infection
Macro Biologics, Inc.44 enrolled4 locationsNCT07379684
Recruiting
Phase 1
Yoga for Black and Brown Women Who Have Experienced Abuse From an Intimate Partner
Psychological Well-beingIntimate Partner Violence (IPV)Psychological Trauma, Historical
The University of Akron40 enrolled1 locationNCT07546266
Recruiting
Phase 1
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
ImpulsivitySuicidal IdeationMild Traumatic Brain Injury
VA Office of Research and Development55 enrolled1 locationNCT05647044
Recruiting
Phase 1Phase 2
Low-Tech Treatments for Obstructive Sleep Apnea
Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 1
Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1
Post-Traumatic Headache
Yale University12 enrolled1 locationNCT06069791
Recruiting
Phase 1Phase 2
Mitigating PTSD-CUD After Sexual Assault
Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1
Inflammatory Challenge and Fear
Posttraumatic Stress Disorder (PTSD)
University of California, San Francisco288 enrolled1 locationNCT06630884
Recruiting
Phase 1Phase 2
Study of Cannabidiol and Neuroimaging on Stress
StressTraumaEarly Life Adversity
Icahn School of Medicine at Mount Sinai160 enrolled1 locationNCT07278505
Recruiting
Phase 1
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Phase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Mild Traumatic Brain InjuryHeadacheBrain Concussion+1 more
State University of New York - Upstate Medical University60 enrolled1 locationNCT06112093
Recruiting
Phase 1
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Posttraumatic Stress Disorder
Johns Hopkins University40 enrolled1 locationNCT06989957
Not Yet Recruiting
Phase 1
Testing the Safety and Effects of the Psychedelic Psilocin on Wellbeing and Anxiety in People with Ongoing Physical and Mental Health Conditions
Chronic Fatigue SyndromeAnorexia NervosaFibromyalgia+6 more
Tryptamine Therapeutics66 enrolled1 locationACTRN12625000949482
Recruiting
Phase 1
Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury
Traumatic Brain Injury
Kessler Foundation60 enrolled1 locationNCT05716048
Recruiting
Phase 1Phase 2
Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury
Traumatic Brain Injury
University of Arizona90 enrolled1 locationNCT06282965
Recruiting
Phase 1
Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury
Traumatic Brain InjurySubarachnoid Hemorrhage
University of Maryland, Baltimore15 enrolled1 locationNCT06103201
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION
Retinitis PigmentosaMacular DegenerationDiabetic Retinopathy+3 more
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled2 locationsNCT05147701
Recruiting
Phase 1
Alexithymia Intervention for Suicide
SchizophreniaPost Traumatic Stress DisorderSuicide+2 more
VA Office of Research and Development40 enrolled1 locationNCT05724953
Recruiting
Phase 1
Regulation of Emotion, Sleep Extension, and mTBI
Mild Traumatic Brain Injury
Merrimack College60 enrolled1 locationNCT06883006
Recruiting
Phase 1Phase 2
Evaluating the Impact of Adjuvant Use of Beta Blockers on Clinical Outcomes in Patients With Traumatic Brain Injury
TBI (Traumatic Brain Injury)
Mansoura University100 enrolled2 locationsNCT06836856