Phase 3 Trauma Clinical Trials
35 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 35 trials
Recruiting
Phase 3
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
PTSD - Post Traumatic Stress Disorder
Senseye, Inc.1,900 enrolled6 locationsNCT07280065
Recruiting
Phase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Post Traumatic Stress Disorder
Transcend Therapeutics300 enrolled19 locationsNCT07456696
Recruiting
Phase 3
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
Mild Traumatic Brain InjuryAdult Growth Hormone Deficiency
VA Office of Research and Development172 enrolled4 locationsNCT04867317
Recruiting
Phase 3
Repurposing Low-Dose Clonidine for PTSD in Veterans
SleepPTSDPosttraumatic Stress Disorder
Wake Forest University Health Sciences32 enrolled1 locationNCT04877093
Recruiting
Phase 3
Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
Traumatic Brain Injury
London School of Hygiene and Tropical Medicine5,000 enrolled2 locationsNCT04521881
Recruiting
Phase 3
Prehospital Analgesia INtervention Trial (PAIN)
Traumatic Injury
Jason Sperry994 enrolled11 locationsNCT05437575
Recruiting
Phase 3
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
Trauma InjuryHemorrhagic Shock
Philip Spinella1,000 enrolled23 locationsNCT06070350
Recruiting
Phase 3
PRP in ACLR to Prevent PTOA
Post-traumatic OsteoarthritisAnterior Cruciate Ligament InjuriesPRP
Hospital for Special Surgery, New York56 enrolled1 locationNCT05412381
Recruiting
Phase 3
Fibrinogen Early In Severe Trauma StudY II
TraumaHaemorrhagic Shock
Australian and New Zealand Intensive Care Research Centre900 enrolled24 locationsNCT05449834
Recruiting
Phase 3
Silexan in the Treatment Of Posttraumatic Stress Disorder Trial
Post Traumatic Stress Disorder
Deakin University278 enrolled4 locationsNCT06412757
Recruiting
Phase 3
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Venous ThromboembolismPulmonary EmbolismDeep Vein Thrombosis+3 more
University Hospital, Angers1,424 enrolled35 locationsNCT06195540
Recruiting
Phase 3
Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury
Traumatic Brain InjuryMilitary Operations
University of South Florida420 enrolled1 locationNCT06581003
Recruiting
Phase 2Phase 3
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
DepressionPost Traumatic Stress DisorderAnxiety Disorders
University of California, San Diego128 enrolled1 locationNCT06273527
Recruiting
Phase 3
Goal-Directed Sedation in Mechanically Ventilated Infants and Children
Post Traumatic Stress DisorderDeliriumCritical Illness+2 more
Vanderbilt University Medical Center372 enrolled1 locationNCT04801589
Recruiting
Phase 2Phase 3
Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms
Post Traumatic Stress DisorderMild Traumatic Brain InjuryAutonomic Nervous System Disease+2 more
Virginia Commonwealth University148 enrolled1 locationNCT07071350
Recruiting
Phase 3
Saline Versus Balanced Crystalloid in Traumatic Brain Injury
Traumatic Brain Injury (TBI) Patients
University of Louisville600 enrolled1 locationNCT06953674
Recruiting
Phase 3
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
Alzheimer DiseaseChronic Traumatic Encephalopathy
CereMark Pharma, LLC230 enrolled1 locationNCT06254469
Recruiting
Phase 3
ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients
Traumatic Brain InjuryWounds and InjuriesTrauma+3 more
Australian and New Zealand Intensive Care Research Centre2,500 enrolled41 locationsNCT04588311
Recruiting
Phase 3
Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)
Mild Traumatic Brain Injury
Foundation for Advancing Veterans' Health Research146 enrolled2 locationsNCT06333990
Recruiting
Phase 2Phase 3
Human Penile Allotransplantation
Wounds and InjuriesAmputationAmputation, Traumatic+6 more
Johns Hopkins University60 enrolled1 locationNCT02395497