Phase 2 Type 2 Diabetes Mellitus Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 2

A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 2

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Type 2 Diabetes Mellitus
Hoffmann-La Roche240 enrolled51 locationsNCT07112872
Recruiting
Phase 2

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

ObesityWeight LossObese+1 more
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics50 enrolled17 locationsNCT07400588
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

T2DM (Type 2 Diabetes Mellitus)
Ascletis Pharma (China) Co., Limited100 enrolled8 locationsNCT07321678
Recruiting
Phase 2

Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes

ObesityType 2 Diabetes Mellitus (T2DM)Food Effect+1 more
Mankind Pharma Limited68 enrolled1 locationNCT07098663
Recruiting
Phase 2

Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

Type 2 Diabetes Mellitus (T2DM)Type 1 Diabetes MellitusDiabetic Foot Ulcer+3 more
Estar Medical dba Medical Technologies, LTD30 enrolled2 locationsNCT06810726
Recruiting
Phase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621
Recruiting
Phase 2

Low-Dose Pioglitazone in Patients With NASH (AIM 2)

Type 2 Diabetes Mellitus (T2DM)Nonalcoholic Steatohepatitis
University of Florida166 enrolled1 locationNCT04501406
Recruiting
Phase 2

To Assess the Efficacy and Safety of HD-6277 in Adult Patients With Inadequate Control of Type 2 Diabetes Mellitus by Diet and Exercise

Type 2 Diabetes Mellitus (T2DM)
Hyundai Pharm160 enrolled1 locationNCT06647550
Recruiting
Phase 2

Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus

Overweight and ObesityType 2 Diabetes Mellitus
Zhujiang Hospital39 enrolled1 locationNCT05253768
Recruiting
Phase 2

Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)

MetforminT2DM (Type 2 Diabetes Mellitus)SGLT2-Inhibitors
Shinshu University120 enrolled1 locationNCT05469659
Completed
Phase 2

A new combination therapy for the treatment of type 2 diabetes mellitus.

Type 2 Diabetes Mellitus
OzStar Therapeutic Pty Ltd30 enrolled1 locationACTRN12614000836639
Completed
Phase 2

Pilot Study of the Effects of GC811007 Administration on Copper and Trace Metal Metabolism in Non-diabetic Subjects and Patients with Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Protemix Corporation40 enrolled1 locationACTRN12612000293864
Active
Phase 2

A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
ChemoCentryx, Inc.140 enrolled4 locationsACTRN12610000400066