Vaping Clinical Trials

25 recruitingLast updated: May 21, 2026

There are 25 actively recruiting vaping clinical trials across 7 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3. Top locations include San Francisco, California, United States, Toronto, Ontario, Canada, New Haven, Connecticut, United States. Updated daily from ClinicalTrials.gov.


Vaping Trials at a Glance

25 actively recruiting trials for vaping are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in San Francisco, Toronto, and New Haven. Lead sponsors running vaping studies include University of California, San Francisco, Yale University, and IRCCS Ospedale San Raffaele.

Browse vaping trials by phase

About Vaping Clinical Trials

Looking for clinical trials for Vaping? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Vaping trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Vaping clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 25 trials

Recruiting

Early Detection of Vaping-related Vascular Diseases

VapingBlood Vessel Injury
University of Miami90 enrolled1 locationNCT05454267
Recruiting
Phase 1

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine DependenceNicotine Vaping
University of California, San Francisco18 enrolled1 locationNCT05962229
Recruiting
Not Applicable

TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System

VapingSmoking, TobaccoTobacco Use Disorder+1 more
University of Zurich406 enrolled1 locationNCT07568483
Recruiting
Not Applicable

Social Media Support Groups for Adolescent Vaping Cessation

VapingNicotine DependenceVaping Cessation
University of California, San Francisco60 enrolled1 locationNCT07540780
Recruiting
Phase 1

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Nicotine Use DisorderNicotine Vaping
Washington University School of Medicine189 enrolled1 locationNCT05994209
Recruiting

The Canadian Lung Outcomes in Users of Vaping Devices Study

VapingVaping TeensSmall Airways Diseases+2 more
University of British Columbia500 enrolled8 locationsNCT06819969
Recruiting
Not Applicable

The Use of tDCS for Vaping Reduction

VapingAddictionTranscranial Direct Current Stimulation (tDCS)
Centre for Addiction and Mental Health40 enrolled1 locationNCT06885606
Recruiting
Not Applicable

Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study

Vaping
Temple University100 enrolled1 locationNCT06804109
Recruiting

Examining Heavy Metal Exposure and Respiratory Health in Young Adult Electronic Cigarette Users

Heavy Metal Exposure From Vaping
Ohio State University Comprehensive Cancer Center100 enrolled1 locationNCT07215065
Recruiting

Vape Use Among Younger & Older Smokers

VapingSmoking BehaviorsSmoking, Cigarette+1 more
Abramson Cancer Center at Penn Medicine100 enrolled1 locationNCT07214168
Recruiting
Not Applicable

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

Vaping
UNC Lineberger Comprehensive Cancer Center3,500 enrolled1 locationNCT07116837
Recruiting
Phase 2

Kick-Nic! Youth Quit Vaping App

Nicotine Vaping
Yale University306 enrolled1 locationNCT06662305
Recruiting
Not Applicable

Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol

VapingVascular Stiffness
University of California, Los Angeles12 enrolled1 locationNCT04661683
Recruiting
Phase 2

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

VapingCannabis UseCannabis Smoking+3 more
University of California, San Francisco48 enrolled1 locationNCT05999383
Recruiting
Phase 2

A Trial of Varenicline for E-cigarette Cessation

VapingE-cigarette useNicotine Dependence
Yale University326 enrolled2 locationsNCT07040566
Recruiting
Not Applicable

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

Cognitive ImpairmentCannabis UseTHC+2 more
University of California, San Francisco110 enrolled1 locationNCT06077292
Recruiting
Not Applicable

Behavioral Intervention for Youth to Promote Vaping Cessation

VapingNicotine DependenceVaping Teens
Massachusetts General Hospital400 enrolled1 locationNCT06765291
Recruiting
Not Applicable

Implementing an Adolescent and Young Adult (AYA) mHealth Vaping Cessation Program Into Oncology Clinics

VapingVaping Cessation
St. Jude Children's Research Hospital500 enrolled1 locationNCT05967585
Recruiting
Not Applicable

Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

Nicotine Vaping
University of Colorado, Denver1,166 enrolled1 locationNCT07009509
Recruiting
Phase 3

Nicotine Patch Plus Nicotine Mouth Spray Versus Nicotine Reduction for Vaping Cessation

Vaping Cessation
University of Auckland, New Zealand774 enrolled1 locationNCT06832098