Vascular Dysfunction Clinical Trials

5 recruiting

Frequently Asked Questions

Common questions about Vascular Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 31 trials

Recruiting

Coronary Flow During Rapid Heart Rates

Heart FailureCoronary Artery DiseaseVentricular Tachycardia+1 more
Imperial College London70 enrolled1 locationNCT05841199
Recruiting
Not Applicable

PMPR and Chlorhexidine on Periodontal Disease and Vascular Function

Vascular DysfunctionCardio Vascular DiseasePeriodontal Disease (PD)+2 more
Mahdi Mutahar30 enrolled1 locationNCT07311512
Recruiting

Vascular Disease Discovery Protocol

Vascular DysfunctionGenetic PredispositionGenetic Mutations
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT03538639
Recruiting

A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

Coronary Microvascular DysfunctionHeart Failure With Preserved Ejection Fraction
Mayo Clinic25 enrolled1 locationNCT07093528
Recruiting

World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach (CaRVD)

Cardiorespiratory and Vascular DysfunctionObstructive Airway Disease
NYU Langone Health100 enrolled1 locationNCT05215171
Recruiting
Not Applicable

Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study)

Coronary Microvascular Dysfunction
VahatiCor, Inc.30 enrolled2 locationsNCT06991322
Recruiting

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Kidney TransplantChronic Kidney DiseaseInflammation+1 more
Brigham and Women's Hospital80 enrolled1 locationNCT07222683
Recruiting
Phase 2

Improving Coronary Vascular Health in Women

Metabolic DiseaseHIV-1-infectionCoronary Microvascular Dysfunction
Massachusetts General Hospital80 enrolled1 locationNCT06843902
Recruiting
Not Applicable

DNA Methylation and Vascular Function

Vascular DysfunctionObesity
University of Illinois at Chicago80 enrolled1 locationNCT03527420
Recruiting
Phase 4

A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculation.

Coronary Microvascular Dysfunction
Peking University First Hospital70 enrolled1 locationNCT05984537
Recruiting

Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic

Microvascular DysfunctionMicrovascular AnginaMINOCA+4 more
University Hospital, Motol1,000 enrolled1 locationNCT07103317
Recruiting

Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution

Microvascular ObstructionCoronary Microvascular DysfunctionST Elevation Myocardial Infarction
The Cleveland Clinic70 enrolled1 locationNCT06795035
Recruiting

Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF

Heart Failure With Preserved Ejection Fraction (HFpEF)Coronary Microvascular Dysfunction
Cedars-Sinai Medical Center180 enrolled2 locationsNCT03876223
Recruiting
Not Applicable

Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility Study

Coronary Microvascular Dysfunction (CMD)Microvascular Coronary DysfunctionMicrovascular Angina
Royal United Hospitals Bath NHS Foundation Trust40 enrolled2 locationsNCT06681896
Recruiting
Not Applicable

Prognostic Role of the Uremic Toxin Indoxyl Sulfate on Vascular and Cardiac Functions During Acute Kidney Injury

Vascular DysfunctionAcute Kidney InjuryUremic; Toxemia
Centre Hospitalier Universitaire, Amiens105 enrolled1 locationNCT05659589
Recruiting
Phase 4

The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

Stable Angina PectorisCoronary Artery DiseaseCoronary Microvascular Dysfunction+1 more
Tina Vilsbøll124 enrolled3 locationsNCT06606821
Recruiting

INOCA-NA a Local Prospective Registry

Coronary Microvascular Dysfunction (CMD)Non-Obstructive Coronary AtherosclerosisMicrocirculatory Status+1 more
Federico II University250 enrolled1 locationNCT06588244
Recruiting

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Myocardial InfarctionCoronary Microvascular DysfunctionVasospasm, Coronary
Chonnam National University Hospital150 enrolled1 locationNCT05272618
Recruiting

PRospective Observation on CErebral microvaScular Structure and Function

Cardiovascular DiseasesCognitive DysfunctionCerebrovascular Disorders+3 more
Beijing Tiantan Hospital3,500 enrolled2 locationsNCT06579677
Recruiting

Cardiac Magnetic Resonance Stress-perfusion Study in Patinets with Fontan Circulation

Heart FailureUniventricular HeartMicrovascular Dysfunction+1 more
Karolinska Institutet30 enrolled1 locationNCT06735521