Centre Hospitalier de l'Université de Montréal

Montreal, Quebec, Canada

26 recruiting

Showing 120 of 41 trials

Recruiting
Phase 3

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Breast Cancer
Pfizer400 enrolled384 locationsNCT07062965
Recruiting
Phase 2Phase 3

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Breast Neoplasms
Bristol-Myers Squibb500 enrolled294 locationsNCT06926868
Recruiting
Phase 3

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Pfizer600 enrolled233 locationsNCT06551324
Recruiting
Not Applicable

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting

Corneal Melting in Boston Keratoprosthesis Type I
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT03041883
Recruiting
Not Applicable

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

ALS (Amyotrophic Lateral Sclerosis)ALSFTDFrontal Temporal Dementia (FTD)
Centre hospitalier de l'Université de Montréal (CHUM)150 enrolled1 locationNCT06051123
Recruiting
Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Prostate CancerCancer of the ProstateHormone Sensitive Prostate Cancer+1 more
Pfizer1,000 enrolled295 locationsNCT07028853
Recruiting
Phase 1Phase 2

Topical Infliximab in Eyes With Penetrating Keratoplasty

Glaucoma Following Surgery
Centre hospitalier de l'Université de Montréal (CHUM)50 enrolled1 locationNCT05180994
Recruiting
Phase 3

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Endometrial Cancer
Karyopharm Therapeutics Inc276 enrolled217 locationsNCT05611931
Recruiting
Not Applicable

WATER IV Prostate Cancer

Localized Prostate Cancer
PROCEPT BioRobotics280 enrolled37 locationsNCT06651632
Recruiting
Phase 3

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Metastatic Castration-resistant Prostate Cancer
Pfizer900 enrolled241 locationsNCT06629779
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Non-small Cell Lung Cancer (NSCLC)High-grade Serous Ovarian Carcinoma (HGSOC)Uterine Serous Carcinoma (USC)
Bristol-Myers Squibb240 enrolled17 locationsNCT06476808
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

Breast CancerLung Cancer
Bristol-Myers Squibb416 enrolled63 locationsNCT06618287
Recruiting

Prevalence of Postpartum Depression Among Patients of the CHUM GARE Clinic

Mental Health IssueMaternal HealthPost Partum Depression
Centre hospitalier de l'Université de Montréal (CHUM)100 enrolled1 locationNCT07200323
Recruiting
Phase 2

Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC

Non-small Cell Lung CancerStage III Lung Cancer
Centre hospitalier de l'Université de Montréal (CHUM)118 enrolled1 locationNCT06878274
Recruiting
Phase 3

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled101 locationsNCT04045665
Recruiting
Phase 4

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

Atrial FibrillationStroke
Population Health Research Institute2,270 enrolled105 locationsNCT03968393
Recruiting
Phase 2

Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)

Older PeopleDrug TherapyInsomnia Chronic
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT06983080
Recruiting
Phase 1

A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

Advanced Solid Tumors
Bristol-Myers Squibb213 enrolled11 locationsNCT06544655
Recruiting
Not Applicable

Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer

Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity CancerHead &Amp;Amp; Neck Squamous Cell CarcinomaLarynx Squamous Cell Carcinoma
Centre hospitalier de l'Université de Montréal (CHUM)85 enrolled1 locationNCT07180901
Recruiting
Not Applicable

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

Coronary Artery DiseaseAortic StenosisCoronary Stenosis
University of British Columbia4,000 enrolled72 locationsNCT04634240