Affective Disorder Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Affective Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 56 trials

Recruiting
Not Applicable

Cerebellar Modulation of Cognition in Psychosis

SchizophreniaPsychosisSchizoaffective Disorder+1 more
Mclean Hospital95 enrolled2 locationsNCT06107764
Recruiting
Phase 1Phase 2

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Not Applicable

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

Schizo Affective DisorderSCHIZOPHRENIA 1 (Disorder)
Nathan Kline Institute for Psychiatric Research120 enrolled1 locationNCT07469384
Recruiting
Not Applicable

Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study

SchizophreniaControl SubjectsSchizoaffective Disorder
Rutgers, The State University of New Jersey74 enrolled1 locationNCT06745479
Recruiting

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

SchizophreniaSchizoaffective DisorderDelusional Disorder+4 more
Beth Israel Deaconess Medical Center320 enrolled6 locationsNCT06740383
Recruiting
Phase 4

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

ObesityWeight LossBipolar I Disorder+3 more
Mayo Clinic100 enrolled1 locationNCT07213466
Recruiting
Not Applicable

Prebiotic Treatment in People With Schizophrenia

SchizophreniaSchizoaffective Disorder
University of Maryland, Baltimore60 enrolled1 locationNCT05527210
Recruiting
Not Applicable

Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders

SchizophreniaSchizophrenia Spectrum DisordersPsychotic Disorders+3 more
Charite University, Berlin, Germany60 enrolled1 locationNCT07395206
Recruiting
Not Applicable

Enhanced Coordinated Specialty Care for Early Psychosis

SchizophreniaBipolar DisorderPsychosis+2 more
Mclean Hospital350 enrolled5 locationsNCT06071858
Recruiting
Not Applicable

Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness (R33)

Schizoaffective DisorderSchizophenia Disorder
University of California, San Diego125 enrolled1 locationNCT06865937
Recruiting
Phase 3

Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.

Bipolar Affective Disorder
University of Sao Paulo40 enrolled1 locationNCT07412132
Recruiting
Phase 4

Anticholinergic Deprescription in Schizophrenia

SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.105 enrolled1 locationNCT06562608
Recruiting

Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients

Schizophrenia DisordersPersonality DisordersDepression Disorders+1 more
University of Edinburgh100 enrolled1 locationNCT07398365
Recruiting
Not Applicable

CBT-CP for Veterans With SMI

Chronic PainSchizophreniaPsychotic Disorders+2 more
VA Office of Research and Development190 enrolled1 locationNCT06758414
Recruiting
Phase 4

CLOZAPINE Response in Biotype-1

SchizophreniaSchizoaffective DisorderBipolar 1 Disorder
University of Texas Southwestern Medical Center524 enrolled5 locationsNCT04580134
Recruiting
Not Applicable

Magnetic Seizure Therapy for Schizophrenia - Trial

SchizophreniaTreatment-resistant SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health80 enrolled2 locationsNCT06672588
Recruiting
Not Applicable

Enhancing Rehabilitation for Veterans With Serious Mental Illness

SchizophreniaPTSDBipolar Disorder+3 more
VA Office of Research and Development80 enrolled1 locationNCT06586164
Recruiting
Not Applicable

Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial

SchizophreniaSchizoaffective Disorder
Singapore Institute of Technology160 enrolled5 locationsNCT06286202
Recruiting
Phase 4

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

SchizophreniaSchizoaffective Disorder
New York State Psychiatric Institute280 enrolled7 locationsNCT05208190
Recruiting
Not Applicable

Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy

Schizophrenia DisordersSchizoaffective DisorderPsychotic Disorder
University of California, San Diego201 enrolled3 locationsNCT07098169