Affective Disorder Clinical Trials

1 recruiting

Affective Disorder Trials at a Glance

59 actively recruiting trials for affective disorder are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 32 trials, with the heaviest enrollment activity in Belmont, Pittsburgh, and San Diego. Lead sponsors running affective disorder studies include Mclean Hospital, VA Office of Research and Development, and Deepak K. Sarpal, M.D..

Browse affective disorder trials by phase

Treatments under study

About Affective Disorder Clinical Trials

Looking for clinical trials for Affective Disorder? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Affective Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Affective Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting

Database Registry for Neural Network Biomarkers in Psychosis

SchizophreniaSchizoaffective Disorder
University of Texas Southwestern Medical Center1,000 enrolled1 locationNCT01409109
Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled19 locationsNCT07105111
Recruiting
Not Applicable

Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis

SchizophreniaPsychotic DisordersSchizo Affective Disorder
The Royal Ottawa Mental Health Centre52 enrolled1 locationNCT05973110
Recruiting
Phase 1Phase 2

Acetazolamide for Treatment Resistant Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Not Applicable

Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine

SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.30 enrolled1 locationNCT06003036
Recruiting
Phase 2

Synbiotic Compound to Reduce Symptoms of Schizophrenia

SchizophreniaSchizoaffective Disorder
Sheppard Pratt Health System68 enrolled1 locationNCT04226898
Recruiting

Brain Imaging of Cognition Inn Schizophrenia and Depression

Schizophrenia / Schizoaffective Disorder
The Royal Ottawa Mental Health Centre90 enrolled1 locationNCT04159662
Recruiting
Not Applicable

Cerebellar Modulation of Cognition in Psychosis

SchizophreniaPsychosisSchizoaffective Disorder+1 more
Mclean Hospital95 enrolled2 locationsNCT06107764
Recruiting
Phase 1Phase 2

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Not Applicable

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

Schizo Affective DisorderSCHIZOPHRENIA 1 (Disorder)
Nathan Kline Institute for Psychiatric Research120 enrolled1 locationNCT07469384
Recruiting
Not Applicable

Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study

SchizophreniaControl SubjectsSchizoaffective Disorder
Rutgers, The State University of New Jersey74 enrolled1 locationNCT06745479
Recruiting
Phase 4

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

ObesityWeight LossBipolar I Disorder+3 more
Mayo Clinic100 enrolled1 locationNCT07213466
Recruiting

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

SchizophreniaSchizoaffective DisorderDelusional Disorder+4 more
Beth Israel Deaconess Medical Center320 enrolled6 locationsNCT06740383
Recruiting
Not Applicable

Prebiotic Treatment in People With Schizophrenia

SchizophreniaSchizoaffective Disorder
University of Maryland, Baltimore60 enrolled1 locationNCT05527210
Recruiting
Not Applicable

Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders

SchizophreniaSchizophrenia Spectrum DisordersPsychotic Disorders+3 more
Charite University, Berlin, Germany60 enrolled1 locationNCT07395206
Recruiting
Not Applicable

Enhanced Coordinated Specialty Care for Early Psychosis

SchizophreniaBipolar DisorderPsychosis+2 more
Mclean Hospital350 enrolled5 locationsNCT06071858
Recruiting
Not Applicable

Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness (R33)

Schizoaffective DisorderSchizophenia Disorder
University of California, San Diego125 enrolled1 locationNCT06865937
Recruiting
Phase 3

Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.

Bipolar Affective Disorder
University of Sao Paulo40 enrolled1 locationNCT07412132
Recruiting
Phase 4

Anticholinergic Deprescription in Schizophrenia

SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.105 enrolled1 locationNCT06562608
Recruiting

Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients

Schizophrenia DisordersPersonality DisordersDepression Disorders+1 more
University of Edinburgh100 enrolled1 locationNCT07398365