Phase 4 Anaesthesia Clinical Trials
27 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 27 trials
Recruiting
Phase 4
PeRiOperative Medicine Platform Trial
Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4
Effect of Neoadjuvant Chemotherapy on Cardiac Function of Perioperative Patients With Breast Cancer and New Strategies for Anesthesia
Breast CancerNeoadjuvant ChemotherapyPerioperative Period+2 more
Fujian Medical University Union Hospital496 enrolled1 locationNCT06497660
Recruiting
Phase 4
Effect of Dexamethasone on Post-spinal Hypotension
Post Spinal Anaesthesia HypotensionGeriatric PopulationOrthopedic Surgeries
Shaheed Mohtarma Benazir Bhutto Institue of Trauma170 enrolled1 locationNCT06819436
Recruiting
Phase 4
The Effect of Volatile Versus Total Intravenous Anaesthesia (TIVA) on the Inducibility of Tachyarrhythmias During Ventricluar Tachycardia (VT) Ablation Procedures
Anaesthesia
Departments of Anaesthesia, Cardiology - Westmead Hospital24 enrolled2 locationsACTRN12623000825651
Completed
Phase 4
Impact of volatile gas versus intravenous general anaesthetic usage during management of endovascular retrieval of clot in ischaemic stroke on long-term patient outcomes
Anaesthesia
Metro South Health via the Princess Alexandra Hospital58 enrolled1 locationACTRN12621000074897
Not Yet Recruiting
Phase 4
Ultrasound guided hamstring block to reduce autologous graft site pain in hamstring tendon anterior cruciate ligament reconstruction
ACL ruptureAnaesthesia
Dr Hamish Mace88 enrolled1 locationACTRN12620000307909
Recruiting
Phase 4
Does the use of muscle relaxants during anaesthesia for hip arthroscopies influence the pressure on the perineum?
pressure on the pudendal nerveAnaesthesia for hip arthroscopic surgery
Prof. Thomas Ledowski40 enrolled2 locationsACTRN12617000191392
Recruiting
Phase 4
Maternal hypotension during elective caesarean delivery under various spinal anaesthesia regimens
Maternal pulmonary aspirationMaternal arrythmiasMaternal unconsciousness+4 more
University Hospital Gregorio Maranon280 enrolled1 locationACTRN12616000884404
Completed
Phase 4
Low dose versus standard dose oxytocin in pregnant women undergoing elective caesarean delivery
Obstetric anaesthesia for elective caesarean section
Royal Hobart Hospital66 enrolled1 locationACTRN12616000398404
Completed
Phase 4
Comparison of upper airway properties during dexmedetomidine and propofol sedation
anaesthesia safety
Sir Charles Gairdner Hospital20 enrolled1 locationACTRN12616000085471
Completed
Phase 4
A randomized trial of midazolam versus placebo on cognitive recovery in adult patients following elective outpatient colonoscopy using postoperative quality of recovery scale.
Cognitive recovery following anaesthesia
Usha Gurunathan400 enrolled2 locationsACTRN12615000625572
Completed
Phase 4
Effects of Sevoflurane and Desflurane on otoacoustic emissions (OAE) in healthy adult patients with normal hearing tests undergoing septoplasty and turbinoplasty surgery
Otoacoustic emissions in healthy adult patients before, during and following anaesthesia with normal hearing tests
Gurcan Gungor22 enrolled1 locationACTRN12614000758606
Not Yet Recruiting
Phase 4
Investigation of the effects of anaesthetic choice on ventilation-perfusion scatter and lung gas exchange.
Impaired lung function under anaesthesia
Austin Health24 enrolled1 locationACTRN12614000226606
Terminated
Phase 4
A randomised trial of propofol sedation versus desflurane anaesthesia, used to supplement spinal anaesthesia, on the quality of recovery following hip replacement surgery in adult patients
AnaesthesiaHip surgery
The University of Melbourne200 enrolled1 locationACTRN12613000805774
Completed
Phase 4
The Effect of Intranasal Dexmedetomidine Premedication on the Minimum Alveolar Concentration of Sevoflurane for the Insertion of Laryngeal Mask Airway in children
Induction and maintenance of general anaesthesia in children
Yusheng Yao90 enrolled1 locationACTRN12613000462785
Completed
Phase 4
Phenylephrine Infusion in Caesarean section under spinal anaesthetic
hypotension and nausea under spinal anaesthesia
Frankston Hospital56 enrolled1 locationACTRN12613000117718
Completed
Phase 4
A randomised study to see if two drugs that increase blood pressure, namely phenylephrine and metaraminol, are equally effective to preventing blood pressure falls and in resulting in a healthy baby, at the time of spinal anaesthesia for elective caesarean section
Neonatal acid-base status.Anaesthesia for elective caesarean section
King Edward Memorial Hospital for Women180 enrolled1 locationACTRN12612000996864
Completed
Phase 4
Peak plasma propofol levels during endoscopy
Peak level of propofol in plasma during endoscopy with propofol only anaesthesia
Monash Medical Centre10 enrolled1 locationACTRN12612000797875
Not Yet Recruiting
Phase 4
In patients undergoing ultrasound-guided fascia iliaca compartment blockade before knee replacement surgery, does the addition of hyaluronidase to the local anaesthetic solution improve the success rate and hasten the onset of the nerve blockade?
Improving regional anaesthesia efficacy
Dr Andrew Kenneth Lansdown100 enrolled1 locationACTRN12612000401853
Completed
Phase 4
Validation of the Brain Anaesthesia Response (BAR) Monitoring System during Anaesthesia for Cardiac Surgery: a Double-Blinded, Randomised, Controlled Trial using Two Different Doses of Fentanyl.
Depth of anaesthesia
Cortical Dynamics24 enrolled1 locationACTRN12611000978965