Phase 4 Cardiac Surgery Clinical Trials
17 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–17 of 17 trials
Recruiting
Phase 4
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Postoperative PainPain After SurgeryCardiac Surgery Patient
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07472959
Recruiting
Phase 4
Intrapleural Ropivacaine Infusion in Cardiac Surgery
Coronary Artery DiseaseCardiac SurgeryValvular Diseases
Saint Petersburg State University, Russia116 enrolled2 locationsNCT07116343
Recruiting
Phase 4
Colchicine's Effect on Inflammatory Markers
ColchicineInflammation in Cardiac Surgery
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Phase 4
Oral Methadone in Cardiac Surgery
Pain, PostoperativeAnesthesiaCardiac Surgery
Mayo Clinic100 enrolled1 locationNCT07221617
Recruiting
Phase 4
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
Vasodilatory Hypotension During or After Cardiac Surgery
University of Maryland St. Joseph Medical Center100 enrolled1 locationNCT06487585
Recruiting
Phase 4
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
Postoperative DeliriumPostoperative Cognitive DysfunctionMajor Noncardiac Surgery
Medical University of Vienna1,332 enrolled2 locationsNCT05990790
Recruiting
Phase 4
Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery
Vasoplegic Syndrome of Cardiac Surgery
University of Sao Paulo350 enrolled1 locationNCT06934798
Recruiting
Phase 4
Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery
EsketamineDexmedetomidineAdults+2 more
Peking University First Hospital476 enrolled1 locationNCT06859892
Recruiting
Phase 4
Evaluation of Clinical Impact of the Type of Cardioplegia Used in the Patient Undergoing Major Cardiac Surgery.
Cardiac SurgeryHeart ArrestCardioplegia
Lourdes Montero Cruces600 enrolled1 locationNCT06530641
Not Yet Recruiting
Phase 3Phase 4
Factor concentrates versus Allogeneic blood in CardioThoracic Surgery trial
Cardiac Surgery
St Vincent's and Mater Health Sydney140 enrolled1 locationACTRN12615000315516
Completed
Phase 4
The effect of propofol versus etomidate on blood pressure stability in cardiac patients.
Haemodynamic stability during the first 10 minutes of aneathesia for cardiac surgery.
The University of Auckland152 enrolled1 locationACTRN12614000717651
Completed
Phase 4
A single centre nested cohort study investigating the safety and efficacy of using 0.9 % saline or Plasma-Lyte(Registered Trademark) 148 as post-operative fluid therapy in adults undergoing cardiac surgery
Cardiac Surgery
Medical Research Institute of New Zealand260 enrolled1 locationACTRN12614000289617
Not Yet Recruiting
Phase 4
A Pilot, Randomised, Blinded, Feasibility, Safety and Biochemical and Physiological Efficacy Study of Terlipressin vs. Placebo in Cardiac Surgery Patients with the Post-operative High Cardiac Output and Hypotension syndrome
Post-operative high cardiac output and hypotension syndrome in patients following cardiac surgery
Austin Health40 enrolled1 locationACTRN12613001194752
Recruiting
Phase 4
Are the lidocaine jelly application to chest tubes effective in relieving the postoperative pain after cardiac surgery?
patients undergoing cardiac surgery
Chung-Ang University40 enrolled1 locationACTRN12611001215910
Completed
Phase 3Phase 4
Alpha-2 agonists in cardiac kids
Children undergoing cardiac surgery
University of Auckland100 enrolled1 locationACTRN12606000246583
Completed
Phase 3Phase 4
Effect of preoperative atenolol on morality and cardiovascular morbidity after non-cardiac surgery.
Patients undergoing major non-cardiac surgery.
Department of Anaesthesia, St Vincent's Hospital, Melbourne200 enrolled1 locationACTRN12605000639628
Completed
Phase 4
The ATACAS Trial: Aspirin and Tranexamic Acid for Coronary Artery Surgery Trial
Patient undergoing elective CABG surgery for any reason, who are at an increased risk of major complications due to their age, cardiac function, comorbidity, or previous cardiac surgery.
The Alfred Hospital4,600 enrolled4 locationsACTRN12605000557639