Phase 3 Cardiac Surgery Clinical Trials
17 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–17 of 17 trials
Recruiting
Phase 3
Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery
Bariatric SurgeryCardiac Surgery With Sternotomy
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07539623
Recruiting
Phase 3
Evaluation of Analgesia for Cardiac Elective Surgery in Children
Pediatric Cardiac Surgery
Senthil Sadhasivam500 enrolled1 locationNCT06626035
Recruiting
Phase 3
Desflurane vs. Propofol for Cardiac Anesthesia
Coronary Artery Bypass GraftingCardiac Surgery
Xijing Hospital3,560 enrolled14 locationsNCT07116733
Recruiting
Phase 3
The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial
Bleeding Post Cardiac SurgeryIndication for Anticoagulation
Population Health Research Institute3,500 enrolled19 locationsNCT04284839
Recruiting
Phase 3
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
Cardiac SurgeryVasoplegia
Universität Münster1,022 enrolled4 locationsNCT06615102
Recruiting
Phase 3
Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
Cardiac SurgeryCardiopulmonary BypassNitric Oxide+1 more
Xijing Hospital3,650 enrolled3 locationsNCT06702553
Recruiting
Phase 3
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Cardiac Surgery
Assistance Publique - Hôpitaux de Paris220 enrolled9 locationsNCT04075981
Recruiting
Phase 3
Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery
Cardiovascular DiseasesCardiovascular ComplicationMyocardial Injury+2 more
Cantonal Hospital of St. Gallen880 enrolled1 locationNCT06279000
Recruiting
Phase 3
Managing Delirium with FLUvoxamine treatment in Non-Cardiac Surgical patients: a feasibility trial
Non-Cardiac SurgeryDelirium
Royal Prince Alfred Hosptial46 enrolled2 locationsACTRN12622000862741
Not Yet Recruiting
Phase 3Phase 4
Factor concentrates versus Allogeneic blood in CardioThoracic Surgery trial
Cardiac Surgery
St Vincent's and Mater Health Sydney140 enrolled1 locationACTRN12615000315516
Recruiting
Phase 3
Colchicine for the Primary Prevention of Atrial Fibrillation after Cardiac Surgery: A Double Blind Placebo Randomised Controlled Trial
Postoperative Atrial Fibrillation after Cardiac Surgery
Barwon Health - The Geelong Hospital520 enrolled1 locationACTRN12613001345774
Not Yet Recruiting
Phase 3
Vitamin D status in heart surgery patients and effects on clinical outcomes
Elective cardiac surgery patients requiring either or both coronary artery bypass graft or valve repair or replacement
The Alfred100 enrolled1 locationACTRN12611000516987
Completed
Phase 3Phase 4
Alpha-2 agonists in cardiac kids
Children undergoing cardiac surgery
University of Auckland100 enrolled1 locationACTRN12606000246583
Active
Phase 2Phase 3
Dietary fish oil and post surgical atrial fibrillation
Atrial fibrillation post cardiac surgery
Royal Adelaide Hospital600 enrolled1 locationACTRN12606000134527
Recruiting
Phase 3
Preoperative intranenous N-Acetylcysteine for the prevention of renal failure in patients with renal impairment undergoing cardiac surgery
Renal Impairment in cardiac surgery
Prince of Wales Hospital200 enrolled1 locationACTRN12606000088549
Completed
Phase 3Phase 4
Effect of preoperative atenolol on morality and cardiovascular morbidity after non-cardiac surgery.
Patients undergoing major non-cardiac surgery.
Department of Anaesthesia, St Vincent's Hospital, Melbourne200 enrolled1 locationACTRN12605000639628
Recruiting
Phase 2Phase 3
The effect of heparin on lung function following cardiopulmonary bypass.
Lung injury following cardiac surgery.
Nil30 enrolled1 locationACTRN12605000133639