Phase 3 Cervical Cancer Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)
Cervical Cancer
Merck Sharp & Dohme LLC686 enrolled240 locationsNCT06459180
Recruiting
Phase 3
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
Cervical Cancer
Merck Sharp & Dohme LLC1,023 enrolled87 locationsNCT07216703
Recruiting
Phase 3
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Stage IIIA Cervical Cancer FIGO 2018Stage IIIB Cervical Cancer FIGO 2018Locally Advanced Cervical Adenocarcinoma+5 more
National Cancer Institute (NCI)336 enrolled222 locationsNCT07061977
Recruiting
Phase 3
Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
Locally Advanced Cervical Cancer
AstraZeneca800 enrolled204 locationsNCT06079671
Recruiting
Phase 3
A Phase III Clinical Study of Adebrelimab Combined With Concurrent Chemoradiotherapy Versus Placebo Combined With Concurrent Chemoradiotherapy for the Treatment of Locally Advanced Cervical Cancer
Advanced Cervical Cancer
Shanghai Shengdi Pharmaceutical Co., Ltd720 enrolled1 locationNCT07168200
Recruiting
Phase 3
A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer
Recurrent Cervical CancerMetastatic Cervical Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.398 enrolled1 locationNCT07418749
Recruiting
Phase 2Phase 3
PD-1 (Programmed Death-1) Versus PD-L1 (Programmed Death-ligand 1) Immune Check Point Inhibitors Combined With Chemotherapy, With or Without Bevacizumab, In Patients With Metastatic, Persistent Or Recurrent Cervical Cancer
Recurrent Cervical CancerMetastatic Cervical CancerPersistent Cervical Cancer
N.N. Alexandrov National Cancer Centre120 enrolled1 locationNCT07472153
Recruiting
Phase 2Phase 3
Extended-field Proton Therapy for Cervical Cancer
Cervical Cancer
National Taiwan University Hospital44 enrolled2 locationsNCT07298642
Recruiting
Phase 2Phase 3
Trop2-targeted immunoPET Imaging of Solid Tumors
Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3
Evaluation of Concomitant Chemo-radiotherapy With Cisplatine vs Gemcitabin in Locally Advanced Cervicouterine Cancer
Locally Advanced Cervical CancerGemcitabineChemo-radiotherapy
National Institute of Cancerología140 enrolled1 locationNCT06156514
Recruiting
Phase 3
Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer
Cervical Cancer
Lee's Pharmaceutical Limited440 enrolled5 locationsNCT06459687
Recruiting
Phase 3
Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer
Cervical CancerAdaptive Radiotherapy
Peking Union Medical College Hospital440 enrolled1 locationNCT06641635
Recruiting
Phase 2Phase 3
BAT1308 Combined with Platinum-Based Chemotherapy± Bevacizumab for PDL1-Positive (CPS ≥1) Cervical Cancer
Cervical Cancer
Bio-Thera Solutions526 enrolled1 locationNCT06123884
Recruiting
Phase 3
A Study to Evaluate 9MW2821 Versus Treatment of Physician's Choice for Subjects With Recurrent or Metastatic Cervical Cancer
Cervical Cancer
Mabwell (Shanghai) Bioscience Co., Ltd.420 enrolled2 locationsNCT06692166
Recruiting
Phase 2Phase 3
Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC
Cervical CancerConcurrent ChemoradiotherapyNeoadjuvant Chemoimmunotherapy+1 more
Tongji Hospital440 enrolled12 locationsNCT06288373
Recruiting
Phase 3
Adjuvant Chemotherapy in cfHPV-DNA Plasma Positive Patients: A Biomarker In Locally Advanced Cervical Cancer
Cervical CancerCervix CancerCervix Neoplasm
Hospital do Coracao365 enrolled26 locationsNCT05764044
Recruiting
Phase 2Phase 3
Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors
Breast CancerOvarian CancerCervical Cancer+7 more
Second Affiliated Hospital of Guangzhou Medical University200 enrolled1 locationNCT03755739
Recruiting
Phase 3
Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
Cervical CancerVaginal CancerVulvar Cancer+11 more
Shanghai Bovax Biotechnology Co., Ltd.8,000 enrolled1 locationNCT04422366
Recruiting
Phase 3
Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
Cervical CancerVaginal CancerVulvar Cancer+12 more
Shanghai Bovax Biotechnology Co., Ltd.1,200 enrolled1 locationNCT04895020
Recruiting
Phase 3
Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years
Vaginal CancerCIN1CIN2+4 more
Shanghai Bovax Biotechnology Co., Ltd.1,348 enrolled1 locationNCT05027776