Coagulation Clinical Trials

8 recruiting

Frequently Asked Questions

Common questions about Coagulation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 46 trials

Recruiting
Phase 1

A Study to Assess the Safety and Effects of Different Doses of an Investigational Drug, BAY 3389934, in Healthy Japanese Volunteers.

Sepsis Associated Disseminated Intravascular Coagulation (DIC)
Bayer16 enrolled2 locationsNCT07176728
Recruiting

Italian Retrospective/Prospective Observational Study on Prosthetic Surgery in Patients With Congenital Coagulation Diseases (MEC).

Prosthetic SurgeryCongenital Coagulation Diseases
Fondazione IRCCS Policlinico San Matteo di Pavia425 enrolled1 locationNCT07494344
Recruiting

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

Inflammatory Bowel DiseasesHeart DiseasesAutoimmune Disease+5 more
University of Chicago1,200 enrolled1 locationNCT01280825
Recruiting

External Multicenter Validation of the APTTO Model for Prolonged APTT Using Clot Waveform Analysis

Coagulation Disorder, BloodProlonged APTT
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz1,500 enrolled16 locationsNCT07418099
Recruiting
Not Applicable

Contact Activation of Coagulation in Newly Inserted Central Venous Catheters

CoagulationCentral Venous CatheterCoagulation Activation+1 more
Thomas Kander88 enrolled1 locationNCT07014722
Recruiting
Phase 3

A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery

Coagulation Disorder
Takeda328 enrolled64 locationsNCT05156983
Recruiting
Not Applicable

Study Protocol: Impact of Metamizole (Optalgin®) on Anti-Xa Concentrations in Oncology Patients Receiving DOACs

Pain ManagementOncologic DiseasesCoagulation Defect
Rambam Health Care Campus30 enrolled1 locationNCT07384013
Recruiting

Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

CoagulationCongenital Heart Disease
Boston Children's Hospital100 enrolled1 locationNCT04299828
Recruiting
Phase 2

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Venous Thromboembolic DiseaseAutoimmune Hemolytic AnemiaProlonged Anticoagulation
Centre Hospitalier Universitaire Dijon72 enrolled1 locationNCT05089227
Recruiting
Phase 3

Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

Acute Kidney Injury (AKI)Regional Citrate Anticoagulation (RCA)Continuous Renal Replacement Therapy (CRRT)
Vantive Health LLC40 enrolled14 locationsNCT05399537
Recruiting
Phase 4

Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy

AnticoagulationCoronary Endarterectomy
China National Center for Cardiovascular Diseases202 enrolled1 locationNCT05782270
Recruiting

Investigation of the Genetics of Hematologic Diseases

Diamond-Blackfan AnemiaDyskeratosis CongenitaFanconi Anemia+10 more
St. Jude Children's Research Hospital1,716 enrolled1 locationNCT02720679
Recruiting
Phase 3

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial

Bleeding Post Cardiac SurgeryIndication for Anticoagulation
Population Health Research Institute3,500 enrolled19 locationsNCT04284839
Recruiting

Clinical Performance Evaluation of Native Whole Blood Samples of Patients on DOACs With the Perosphere ClotChek™

Coagulation
Perosphere Technologies Inc.150 enrolled4 locationsNCT07012291
Recruiting
Not Applicable

Comparative Study of Tranexamic Acid Dosing in Cardiac Surgery

Adverse Drug EventFibrinolysis; HemorrhageBlood Coagulation Disorder+2 more
University of Ioannina150 enrolled1 locationNCT07164300
Recruiting
Not Applicable

Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)

BleedingPercutaneous Coronary InterventionCoronary Angiography+2 more
University Hospital, Strasbourg, France550 enrolled1 locationNCT06890312
Recruiting

Transfusion Surveillance in Anaesthesia

AnesthesiaSide EffectBlood Coagulation Disorder+4 more
Erasme University Hospital50,000 enrolled1 locationNCT06403163
Recruiting

Effects of Different Continuous Renal Replacement Therapy Patterns on Ionized Calcium in Patients With Citrate Anticoagulants Using Calcium-containing Replacement Solutions

Renal InjuryRegional Citrate Anticoagulation
Fujian Provincial Hospital30 enrolled1 locationNCT06021080
Recruiting
Phase 1

Phase I Study of MT1011 Injection in Healthy Subjects

Used in Patients Receiving Anticoagulant Therapy (e.g., Rivaroxaban or Apixaban, Inhibitors of Coagulation Factor Xa) Who Require Reversal of Anticoagulation
Shaanxi Micot Pharmaceutical Technology Co., Ltd.40 enrolled1 locationNCT07024160
Recruiting

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Vitamin K-Dependent Coagulation DefectSignificant Bleeding Risk
Octapharma3,574 enrolled1 locationNCT06429787