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Healthy Volunteers Clinical Trials

273 recruitingLast updated: July 26, 2026

There are 273 actively recruiting healthy volunteers clinical trials across 44 countries. Studies span Phase 1, Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Bethesda, Maryland, United States, Baltimore, Maryland, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Healthy Volunteers Trials at a Glance

273 actively recruiting trials for healthy volunteers are listed on ClinicalTrialsFinder across 6 cities in 44 countries. The largest study group is Phase 1 with 137 trials, with the heaviest enrollment activity in Bethesda, Baltimore, and London. Lead sponsors running healthy volunteers studies include Bristol-Myers Squibb, AbbVie, and Hospices Civils de Lyon.

Browse healthy volunteers trials by phase

Treatments under study

About Healthy Volunteers Clinical Trials

Looking for clinical trials for Healthy Volunteers? There are currently 241 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Healthy Volunteers trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Healthy Volunteers clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 273 trials

Recruiting
Phase 1

Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

Healthy VolunteersDengueHuman Challenge Trial
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled1 locationNCT07706686
Recruiting
Not Applicable

Analytical Validation of Circulating DNA Analysis Methods: Creation of a Control Cohort

Healthy Volunteers (Cancer)
Institut Claudius Regaud68 enrolled1 locationNCT07663994
Recruiting
Phase 1

A Study to Assess Safety, Tolerability, and How Single and Multiple Injections or Infusions of ABBV-313 Affects the Body of Adult Participants

Healthy Volunteers
AbbVie64 enrolled1 locationNCT07673120
Recruiting
Phase 1

Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants

Healthy Volunteers
Bristol-Myers Squibb136 enrolled1 locationNCT07629999
Recruiting
Not Applicable

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)700 enrolled1 locationNCT03258580
Recruiting
Not Applicable

Mechanism of Non-invasive Magnetic Stimulation

Healthy Volunteers
National Institute on Drug Abuse (NIDA)95 enrolled1 locationNCT03394066
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting
Phase 1

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Healthy Volunteers
Intra-Cellular Therapies, Inc.42 enrolled1 locationNCT06299410
Recruiting

Sample Collection From Healthy Volunteers for Assay Optimization

Healthy Volunteers
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT03538600
Recruiting
Phase 1

A Study to Evaluate ALN-4915 in Adult Healthy Volunteers

Healthy Volunteers
Alnylam Pharmaceuticals44 enrolled1 locationNCT07535606
Recruiting
Phase 1

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants

Healthy Volunteers
Hoffmann-La Roche128 enrolled1 locationNCT07271693
Recruiting
Phase 1

A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Healthy Volunteers
BeOne Medicines30 enrolled1 locationNCT07590102
Recruiting
Phase 2

Gut Microbiome and Metabolic Health Study

Healthy Volunteers
RDC Clinical Pty Ltd90 enrolled1 locationNCT07457723
Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled87 locationsNCT06649110
Recruiting
Not Applicable

Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training

Muscle hypertrophyHealthy VolunteersGlycolysis+1 more
Technical University of Munich120 enrolled8 locationsNCT07721766
Recruiting
Phase 4

Vitamin B12 Absorption Study

Healthy Volunteers
RDC Clinical Pty Ltd12 enrolled1 locationNCT07665671
Recruiting
Phase 1

A Dose-Escalation Study of RO7875913 in Healthy Participants

Healthy Volunteers
Genentech, Inc.40 enrolled1 locationNCT07342114
Recruiting
Not Applicable

Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes.

Healthy VolunteersNeuromuscular Function
Universitat Internacional de Catalunya23 enrolled1 locationNCT07719179
Recruiting
Phase 1

Study Evaluating Safety & Tolerability of Migaldendranib in Healthy Volunteers

Healthy Volunteers
Ashvattha Therapeutics, Inc.36 enrolled1 locationNCT07370155
Recruiting

Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers

Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT00442195