Lidocaine Clinical Trials

11 recruitingLast updated: May 21, 2026

There are 11 actively recruiting lidocaine clinical trials across 4 countries. Studies span Not Applicable, Phase 3. Top locations include Cairo, Egypt, Tanta, El-Gharbia, Egypt, Alexandria, Egypt. Updated daily from ClinicalTrials.gov.


Lidocaine Trials at a Glance

11 actively recruiting trials for lidocaine are listed on ClinicalTrialsFinder across 5 cities in 4 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Cairo, Tanta, and Alexandria. Lead sponsors running lidocaine studies include Tanta University, Cairo University, and Ain Shams University.

Browse lidocaine trials by phase

About Lidocaine Clinical Trials

Looking for clinical trials for Lidocaine? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Lidocaine trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Lidocaine clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 3

Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.

AnalgesiaIntensive Care UnitLidocaine
Centre Hospitalier Universitaire, Amiens70 enrolled1 locationNCT03984656
Recruiting

Outpatient Midline Catheter in Patients Receiveing Lidocaine Infusion Series.

Chronic PainOutpatientLidocaine Infusion+1 more
Medical University of Warsaw500 enrolled1 locationNCT07555314
Recruiting
Not Applicable

Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

Coronary Artery Disease (CAD)FentanylLeft Ventricular (LV) Systolic Dysfunction+4 more
Cairo University40 enrolled1 locationNCT07248202
Recruiting
Not Applicable

Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy

Bariatric SurgeryDexmedetomidineLidocaine
Alexandria University40 enrolled1 locationNCT07327905
Recruiting
Not Applicable

Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

Cerebral oxygen saturationDexmedetomidineElderly Patients+4 more
Tanta University100 enrolled1 locationNCT07108764
Recruiting
Not Applicable

Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy

Cerebral Oxygenationlaparoscopic hysterectomyPropofol+3 more
Tanta University90 enrolled1 locationNCT07062367
Recruiting
Not Applicable

Effect of Oral Melatonin Versus Intraoperative Lidocaine Infusion on Incidence of Postoperative Delirium in Elderly Patients Undergoing Total Hip Arthroplasty

Elderly PatientsPostoperative DeliriumTotal Hip Arthroplasty+2 more
Tanta University135 enrolled1 locationNCT06768580
Recruiting
Not Applicable

Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy

MastectomyDexmedetomidineChronic Pain+4 more
Cairo University90 enrolled1 locationNCT06910644
Recruiting
Not Applicable

Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery

Functional endoscopic sinus surgeryIntraoperative BleedingDexmedetomidine+2 more
Ain Shams University40 enrolled1 locationNCT06848764
Recruiting
Not Applicable

Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

DexmedetomidineVideo-assisted Thoracoscopic SurgeryLidocaine+2 more
Ain Shams University75 enrolled1 locationNCT06837519
Recruiting

Serum lidocaine levels following administration of topical lidocaine during in office laryngopharyngeal procedures

lidocaine toxicity
Auckland District Health Board50 enrolled1 locationACTRN12616000058471