Phase 2 Overweight Clinical Trials
44 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 44 trials
Recruiting
Phase 2
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 2
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 2
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Overweight or Obesity
Regeneron Pharmaceuticals120 enrolled3 locationsNCT07431086
Recruiting
Phase 2
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
ObesityOverweight
Kailera320 enrolled2 locationsNCT07497880
Recruiting
Phase 2
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled15 locationsNCT07441252
Recruiting
Phase 2
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
ObesityOverweight
Novo Nordisk A/S333 enrolled3 locationsNCT07395687
Recruiting
Phase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
ObesityOverweight
Eli Lilly and Company1,217 enrolled53 locationsNCT06143956
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 2
MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity
Insulin ResistancePrediabetesOverweight/Obesity
Hudson Biotech120 enrolled1 locationNCT07505745
Recruiting
Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled38 locationsNCT07215559
Recruiting
Phase 2
A Mobile Intervention to Reduce Pain and Improve Health-III
Obesity and OverweightChronic PainOsteoarthritis+1 more
Wake Forest University200 enrolled1 locationNCT06623669
Recruiting
Phase 1Phase 2
Pilot Testing a Novel Approach to Pediatric Obesity Treatment
Obese AdolescentsOverweight Adolescents
Texas Tech University30 enrolled1 locationNCT06755827
Recruiting
Phase 2
Semaglutide for Post-Smoking Cessation Weight Management
ObesityOverweightCigarette Smoking
The University of Texas Health Science Center, Houston197 enrolled2 locationsNCT06173778
Recruiting
Phase 1Phase 2
The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment
ElderlyMild Cognitive ImpairmentOverweight or Obesity
Fudan University54 enrolled1 locationNCT07395960
Recruiting
Phase 1Phase 2
A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity
Weight ManagementOverweight and/or Obesity
Hangzhou Sciwind Biosciences Co., Ltd.84 enrolled1 locationNCT07243171
Recruiting
Phase 2
Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
ObesityOverweightOverweight and Obesity+2 more
Memorial Sloan Kettering Cancer Center1,785 enrolled1 locationNCT05770570
Recruiting
Phase 2
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
AsthmaOverweight and ObesityAsthma Chronic
Johns Hopkins University100 enrolled2 locationsNCT06273072
Recruiting
Phase 2
A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or Obesity
ObesityOverweight
Novo Nordisk A/S220 enrolled2 locationsNCT07184632
Recruiting
Phase 2
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 2
The Efficacy and Safety of Efsubaglutide Alfa in Overweight/Obesity（SPARKLE）
Obesity and Overweight
Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.200 enrolled5 locationsNCT07114419