Phase 2 Overweight Clinical Trials
53 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 53 trials
Recruiting
Phase 2
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
ObesityOverweight
Kailera320 enrolled23 locationsNCT07497880
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled22 locationsNCT06845202
Recruiting
Phase 2
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
ObesityBody WeightOverweight+5 more
Pfizer872 enrolled48 locationsNCT07575932
Recruiting
Phase 2
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 2
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled22 locationsNCT07441252
Recruiting
Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled42 locationsNCT07215559
Recruiting
Phase 2Phase 3
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia
Overweight and ObesityAtypical Endometrial HyperplasiaFertility Issues
Xiaojun Chen172 enrolled1 locationNCT05316493
Recruiting
Phase 1Phase 2
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
Overweight and Obesity
Wave Life Sciences USA, Inc.296 enrolled6 locationsNCT06842186
Recruiting
Phase 2
EXploratory Study on Postprandial Energy Metabolism
Obesity and OverweightModerately Obese
Lallemand Health Solutions66 enrolled1 locationNCT06786052
Recruiting
Phase 2
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 1Phase 2
Pilot Testing a Novel Approach to Pediatric Obesity Treatment
Obese AdolescentsOverweight Adolescents
Texas Tech University30 enrolled1 locationNCT06755827
Recruiting
Phase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
ObesityOverweight
Eli Lilly and Company1,481 enrolled53 locationsNCT06143956
Recruiting
Phase 1Phase 2
A Trial to Learn How Safe AZD9550 Monotherapy and Combined With AZD6234 is in People With or Without Type 2 Diabetes Who Are Living With Obesity and Overweight
Overweight and Obesity
AstraZeneca160 enrolled15 locationsNCT06151964
Recruiting
Phase 2
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 2
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Overweight or Obesity
Regeneron Pharmaceuticals120 enrolled3 locationsNCT07431086
Recruiting
Phase 2
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
Obesity, OverweightMobility DisabilityHOMA-IR
Veru Inc.200 enrolled10 locationsNCT07446998
Recruiting
Phase 2
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
ObesityOverweight
Novo Nordisk A/S333 enrolled3 locationsNCT07395687
Recruiting
Phase 2
This is a Multi-centre, Multi-drug, Platform Study in Chinese Participants Living With Obesity / Overweight
Obesity, Overweight
AstraZeneca871 enrolled3 locationsNCT07017179
Recruiting
Phase 2
MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity
Insulin ResistancePrediabetesOverweight/Obesity
Hudson Biotech120 enrolled1 locationNCT07505745
Recruiting
Phase 2
A Mobile Intervention to Reduce Pain and Improve Health-III
Obesity and OverweightChronic PainOsteoarthritis+1 more
Wake Forest University200 enrolled1 locationNCT06623669