Oxaluria Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Oxaluria clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 1Phase 2

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Primary Hyperoxaluria Type 1 (PH1)
Arbor Biotechnologies23 enrolled7 locationsNCT06839235
Recruiting
Phase 2

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

End Stage Renal DiseasePrimary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company28 enrolled18 locationsNCT04580420
Recruiting

Prospective Research Rare Kidney Stones (ProRKS)

Adenine Phosphoribosyltransferase DeficiencyCystinuriaDent Disease+2 more
Mayo Clinic220 enrolled11 locationsNCT02780297
Recruiting

Rare Kidney Stone Consortium Biobank

CystinuriaDent DiseasePrimary Hyperoxaluria+1 more
Mayo Clinic2,000 enrolled1 locationNCT02026388
Recruiting

Rare Kidney Stone Consortium Patient Registry

CystinuriaDent DiseasePrimary Hyperoxaluria+1 more
Mayo Clinic730 enrolled4 locationsNCT00588562
Recruiting
Not Applicable

Gut Kidney Axis in Enteric Hyperoxaluria

Enteric Hyperoxaluria
NYU Langone Health80 enrolled1 locationNCT05124886
Recruiting
Early Phase 1

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Type 1 Primary Hyperoxaluria
RenJi Hospital21 enrolled1 locationNCT06511349
Recruiting
Not Applicable

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

NephrolithiasisKidney StoneUrolithiasis+5 more
University of Alabama at Birmingham40 enrolled2 locationsNCT06330246
Recruiting
Not Applicable

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

HealthyNephrolithiasisKidney Stone+6 more
University of Alabama at Birmingham80 enrolled2 locationsNCT06331546
Recruiting
Not Applicable

Oxalate Excretion Profile in Patients with a Heterozygous Mutation of the AGXT (alanine-glyoxylate Aminotransferase) Gene

Hyperoxaluria (Disorder)
Hospices Civils de Lyon25 enrolled1 locationNCT06283082
Recruiting

National Registry of Rare Kidney Diseases

Denys-Drash SyndromeTuberous SclerosisAutosomal Recessive Polycystic Kidney Disease+81 more
UK Kidney Association35,000 enrolled1 locationNCT06065852
Recruiting
Not Applicable

Genetic Newborn Screening for Cystinosis and Primary Hyperoxaluria

CystinosisPrimary Hyperoxaluria
Cystinose Stiftung200,000 enrolled1 locationNCT05843851