Phase 4 Pain Clinical Trials

247 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 247 trials

Recruiting
Phase 4

PRP vs PRP+Betamethasone vs Betamethasone Injection for Upper Trapezius Myofascial Pain

Trigger Point in Trapezius MuscleMyofascial Pain Dysfunction SyndromeTrigger Points, Myofascial
University of Kyrenia150 enrolled2 locationsNCT07547605
Recruiting
Phase 4

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4

Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy

Postoperative Pain
Wah Medical college , POF hospital106 enrolled1 locationNCT07650760
Recruiting
Phase 4

Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

Pain, PostoperativePharmacokinetics
Milton S. Hershey Medical Center40 enrolled1 locationNCT03737292
Recruiting
Phase 4

Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

Pain, Postoperative
Northwestern University90 enrolled1 locationNCT05351229
Recruiting
Phase 4

Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain

Back Pain
Mayo Clinic76 enrolled5 locationsNCT07632820
Recruiting
Phase 4

Dex & Mastectomy Pain

Post-Mastectomy Chronic Pain Syndrome
McGill University Health Centre/Research Institute of the McGill University Health Centre170 enrolled1 locationNCT07556952
Recruiting
Phase 4

Opioid Use After Laparoscopic Salpingectomy

Opioid UsePost Operative PainSterility, Female
Johns Hopkins University38 enrolled1 locationNCT06434233
Recruiting
Phase 4

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

Sickle Cell Disease (SCD)Vaso-Occlusive Pain Episode in Sickle Cell Disease
University of Pennsylvania65 enrolled2 locationsNCT06665997
Recruiting
Phase 4

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients

AnalgesiaEmergenciesRenal Colic+1 more
Hackensack Meridian Health86 enrolled1 locationNCT05776953
Recruiting
Phase 4

Stanford Pragmatic Effectiveness Comparison

Chronic Pain
Stanford University450 enrolled1 locationNCT04441034
Recruiting
Phase 4

Evaluation of Pain Treatment After Total Knee Arthroplasty

Pain
Vertex Pharmaceuticals Incorporated60 enrolled2 locationsNCT07538570
Recruiting
Phase 4

Better Options for Chronic Cancer Pain

Chronic PainCancer SurvivorOpioid Dependence
VA Office of Research and Development294 enrolled2 locationsNCT06574009
Recruiting
Phase 4

PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty

hip osteoarthritisHip ArthropathyHip Pain Chronic
Poznan University of Medical Sciences90 enrolled1 locationNCT07180979
Recruiting
Phase 4

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Pain, PostoperativeSpine FusionLumbar Spine Degeneration+1 more
University of Southern California140 enrolled1 locationNCT05746143
Recruiting
Phase 4

Regional Blocks for Lateral Condyle Fractures

PainFractures, ClosedHumeral Fractures
University of California, Los Angeles90 enrolled1 locationNCT03796572
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

PECS Study for CIED Implantation Surgery

Pain, PostoperativeAdolescentChild
The Hospital for Sick Children48 enrolled1 locationNCT04577690
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

SurgeryPain, Postoperative
University of Michigan900 enrolled8 locationsNCT05722002
Recruiting
Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306