Phase 4 Pain Clinical Trials

222 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 222 trials

Recruiting
Phase 4

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Pain, PostoperativeSpine FusionLumbar Spine Degeneration+1 more
University of Southern California140 enrolled1 locationNCT05746143
Recruiting
Phase 4

Dex & Mastectomy Pain

Post-Mastectomy Chronic Pain Syndrome
McGill University Health Centre/Research Institute of the McGill University Health Centre170 enrolled1 locationNCT07556952
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

Stanford Pragmatic Effectiveness Comparison

Chronic Pain
Stanford University450 enrolled1 locationNCT04441034
Recruiting
Phase 4

PECS Study for CIED Implantation Surgery

Pain, PostoperativeAdolescentChild
The Hospital for Sick Children48 enrolled1 locationNCT04577690
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

SurgeryPain, Postoperative
University of Michigan900 enrolled8 locationsNCT05722002
Recruiting
Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306
Recruiting
Phase 4

Regional Blocks for Lateral Condyle Fractures

PainFractures, ClosedHumeral Fractures
University of California, Los Angeles90 enrolled1 locationNCT03796572
Recruiting
Phase 4

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

Low Back PainRadiculopathy, Lumbosacral RegionBack Pain With Radiation
Montefiore Medical Center132 enrolled2 locationsNCT05721027
Recruiting
Phase 4

Low Dose Naltrexone for Pain in Patients With HIV

Human Immunodeficiency VirusChronic Neuropathic Pain
Emory University60 enrolled3 locationsNCT05537935
Recruiting
Phase 4

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Pain, PostoperativeGynecologic Surgical ProceduresHysterectomy+1 more
Ying Liu120 enrolled2 locationsNCT04130464
Recruiting
Phase 4

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain
Ain Shams University90 enrolled1 locationNCT04908579
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Postoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106
Recruiting
Phase 4

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

Pain, PostoperativeAnkle Fracture Surgery
Jenna-Leigh Wilson100 enrolled1 locationNCT06949826
Recruiting
Phase 4

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Pain, Postoperative
Boston University75 enrolled1 locationNCT06757075
Not Yet Recruiting
Phase 4

Magnesium sulfate as an adjunct to levobupivacaine in rectus sheath block for colorectal surgery: a randomized controlled study

perioperative pain management
University Hospital Sestre Milosrdnice60 enrolled1 locationACTRN12626000376347
Recruiting
Phase 4

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Postoperative Pain Management
Rhode Island Hospital120 enrolled1 locationNCT07316166
Recruiting
Phase 4

Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy

Pain ManagementPancreatoduodenectomy
Iuliu Hatieganu University of Medicine and Pharmacy93 enrolled1 locationNCT07423650
Recruiting
Phase 4

The Stimulation To Induce Mothers Study

Labor PainOxytocinPhysiologic Effects of Drugs+1 more
Yale University988 enrolled3 locationsNCT05079841
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+1 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819