Phase 3 Pain Clinical Trials

165 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 165 trials

Recruiting
Phase 3

Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children

Chronic PainNeuropathic Pain
University Hospital, Brest46 enrolled10 locationsNCT05997979
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathic pain
Vertex Pharmaceuticals Incorporated1,100 enrolled76 locationsNCT06628908
Recruiting
Phase 3

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Complex Regional Pain Syndrome Type I
Ambros Therapeutics, Inc.270 enrolled12 locationsNCT07210515
Recruiting
Phase 3

RADA16 for Adult Tonsillectomy

Postoperative Pain
Rutgers, The State University of New Jersey134 enrolled2 locationsNCT07060495
Recruiting
Phase 3

Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation

Neuropathic PainChronic Postsurgical Pain
University Hospital, Strasbourg, France60 enrolled1 locationNCT05196503
Recruiting
Phase 2Phase 3

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Interstitial CystitisPainful Bladder SyndromePainful Bladder Syndrome (PBS)
David Sheyn100 enrolled1 locationNCT06096597
Recruiting
Phase 3

Suzetrigine in Total Hip Arthroplasty

Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting
Phase 3

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

Chronic Low Back Pain (CLBP)ObesityOverweight
Eli Lilly and Company586 enrolled40 locationsNCT07035093
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathic pain
Vertex Pharmaceuticals Incorporated734 enrolled75 locationsNCT07231419
Recruiting
Phase 2Phase 3

Virtual Menstrual Pain Approaches in Females

Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Phase 3

Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery

Post Operative PainBariatric SurgeryCardiac Surgery With Sternotomy
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07539623
Recruiting
Phase 3

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled20 locationsNCT07226258
Recruiting
Phase 2Phase 3

"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia

Opioid UsePain, PostoperativeLaparotomy
Sahiwal medical college sahiwal96 enrolled1 locationNCT07590752
Recruiting
Phase 3

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

Opioid misuseChronic PainBack Pain+1 more
Stanford University375 enrolled4 locationsNCT06027099
Recruiting
Phase 3

Management of Moderate to Severe Monotraumatic Pain With Sublingual Sufentanil in an Emergency Situation.

Pain Management
University Hospital, Clermont-Ferrand300 enrolled1 locationNCT06917651
Recruiting
Phase 3

Opioid-Free Orthopaedics

PainPain, Postoperative
Emory University80 enrolled3 locationsNCT04659317
Recruiting
Phase 3

A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management

Cancer Pain
West China Hospital100 enrolled1 locationNCT06663956
Recruiting
Phase 3

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Opioid UsePain, PostoperativePain, Back+1 more
Hospital for Special Surgery, New York150 enrolled1 locationNCT05058287
Not Yet Recruiting
Phase 3

MethoxyFLurane inhaler for single episode cancer-related incident pain in palliative cARE patients: The FLARE feasibility study

Incidental Cancer Pain
Latrobe Regional Health10 enrolled1 locationACTRN12626000499381
Recruiting
Phase 2Phase 3

Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain

Pain, Nerve
Stanford University95 enrolled1 locationNCT06185816