Peripheral Neuropathy Clinical Trials

119 recruitingLast updated: June 17, 2026

There are 119 actively recruiting peripheral neuropathy clinical trials across 34 countries. Studies span Not Applicable, Phase 2, Phase 3, Early Phase 1, Phase 1, Phase 4. Top locations include Houston, Texas, United States, Boston, Massachusetts, United States, Lahore, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Peripheral Neuropathy Trials at a Glance

119 actively recruiting trials for peripheral neuropathy are listed on ClinicalTrialsFinder across 6 cities in 34 countries. The largest study group is Not Applicable with 63 trials, with the heaviest enrollment activity in Houston, Boston, and Lahore. Lead sponsors running peripheral neuropathy studies include M.D. Anderson Cancer Center, Riphah International University, and Bernardino Clavo, MD, PhD.

Browse peripheral neuropathy trials by phase

Treatments under study

About Peripheral Neuropathy Clinical Trials

Looking for clinical trials for Peripheral Neuropathy? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral Neuropathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral Neuropathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 119 trials

Recruiting
Not Applicable

Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

Chemotherapy Induced Peripheral NeuropathyCancerChildhood Cancer
Yale University20 enrolled2 locationsNCT07019259
Recruiting
Not Applicable

The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study

Chemotherapy-induced Peripheral Neuropathy (CIPN)
Luminate Medical, Inc.142 enrolled18 locationsNCT07142304
Recruiting
Not Applicable

WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention

Peripheral NeuropathyDiabetesDiabetic Foot Ulcer+1 more
Johns Hopkins University400 enrolled1 locationNCT05950659
Recruiting
Phase 3

Trial of a Virtual Exercise-based Rehabilitation Program to Treat Persistent Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Chemotherapy-induced Peripheral Neuropathy (CIPN)
University Health Network, Toronto240 enrolled1 locationNCT07481149
Recruiting
Not Applicable

Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy Induced Peripheral NeuropathyCIPN - Chemotherapy-Induced Peripheral Neuropathy
Case Comprehensive Cancer Center90 enrolled1 locationNCT07219472
Recruiting
Not Applicable

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

Diabetic Peripheral NeuropathyLower Extremity Amputee
VA Office of Research and Development15 enrolled1 locationNCT04658693
Recruiting
Not Applicable

Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2

Chemotherapy Induced Peripheral NeuropathyGynecologic Cancer
Duke University190 enrolled4 locationsNCT06139458
Recruiting
Not Applicable

Shortwave Intervention for Diabetic Peripheral Neuropathy: A Randomized, Single-Blind, Sham-Controlled Trial(SIDPN)

Diabetic Peripheral Neuropathy
Chongqing Medical University202 enrolled1 locationNCT07625007
Recruiting
Not Applicable

Ultrasound-Guided Nerve Hydrodissection for Diabetic Lower Limb Entrapment Neuropathy: A Randomized, Single-Blind, Sham-Controlled Trial

Diabetic Peripheral NeuropathyEntrapment Neuropathy
Chongqing Medical University266 enrolled1 locationNCT07625020
Recruiting
Phase 2

Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer

Breast CancerPeripheral Neuropathy
Montefiore Medical Center116 enrolled1 locationNCT07109817
Recruiting
Not Applicable

Prevention of Oxaliplatin-induced Nerve Damage in the Body's Extremities

Colorectal, CancerPeripheral Neuropathy
Vejle Hospital120 enrolled4 locationsNCT05404230
Recruiting

Understanding and Preventing Cortical Mechanisms of Chemotherapy-induced Peripheral Neuropathy

Chemotherapy Induced Peripheral Neuropathy
M.D. Anderson Cancer Center45 enrolled1 locationNCT06389721
Recruiting
Phase 1

CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy Induced Peripheral Neuropathy
Milton S. Hershey Medical Center12 enrolled1 locationNCT07016971
Recruiting
Not Applicable

Plantar Intrinsic Muscles Exercises and Three-dimensional Ankle Foot Exercises Comparative Effect in DPN

Diabetic Peripheral Neuropathy (DPN)
Riphah International University40 enrolled1 locationNCT07576179
Recruiting
Not Applicable

Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy

Hematopoietic and Lymphatic System NeoplasmMalignant Solid NeoplasmChemotherapy Induced Peripheral Neuropathy
Mayo Clinic300 enrolled1 locationNCT06945380
Recruiting
Not Applicable

The Role of TRP Channels in CIPN

Chemotherapy Induced Peripheral Neuropathy
Universitaire Ziekenhuizen KU Leuven240 enrolled1 locationNCT04415892
Recruiting
Not Applicable

Closed Loop Spinal Cord Stimulation for Chemotherapy Induced Peripheral Neuropathy, a Pilot Study.

Peripheral Neuropathy Due to Chemotherapy
M.D. Anderson Cancer Center10 enrolled1 locationNCT06616649
Recruiting
Not Applicable

The Treatment of Painful Diabetic Neuropathy With Diet

Peripheral Neuropathy With Type 2 DiabetesPainful Diabetic Neuropathy (PDN)Vegan Diet
AdventHealth40 enrolled1 locationNCT07509671
Recruiting
Phase 3

Study on the Efficacy and Safety of Mecobalamin in Preventing Taxane-related Peripheral Neuropathy

Peripheral Neuropathy Due to ChemotherapyPeripheral Neuropathy, Chemotherapy-induced
Qinghai Red Cross Hospital326 enrolled4 locationsNCT07423390
Recruiting
Not Applicable

Extracellular Vesicles and Chemotherapy-Induced Peripheral Neuropathy

Breast CancerLung CancerHead and Neck Cancer+3 more
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico120 enrolled1 locationNCT07558447