REM Sleep Behavior Disorder Clinical Trials

17 recruiting

REM Sleep Behavior Disorder Trials at a Glance

22 actively recruiting trials for rem sleep behavior disorder are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Minneapolis, Rochester, and Boston. Lead sponsors running rem sleep behavior disorder studies include Chinese University of Hong Kong, University of Minnesota, and Guy's and St Thomas' NHS Foundation Trust.

Browse rem sleep behavior disorder trials by phase

Treatments under study

About REM Sleep Behavior Disorder Clinical Trials

Looking for clinical trials for REM Sleep Behavior Disorder? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new REM Sleep Behavior Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about REM Sleep Behavior Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Pain Assessment in Patients With Idiopathic Rapid Eye Movement (REM) Sleep Behaviour Disorder

REM Sleep Behavior Disorder (iRBD)Narcolepsy Type 1
University Hospital, Toulouse24 enrolled1 locationNCT07365566
Recruiting

A Multimodal Prospective Cohort Study of Parkinsonism

ParkinsonismREM Sleep Behavior Disorder
Ruijin Hospital640 enrolled1 locationNCT07553845
Recruiting

Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology

Parkinson DiseaseREM Sleep Behavior Disorder
IRCCS San Raffaele230 enrolled1 locationNCT05721911
Recruiting

Unmet Needs Among Patients With Isolated REM Sleep Behavior Disorder (iRBD) and Their Significant Others

REM Sleep Behavior DisorderIsolated REM Sleep Behavior Disorder
Universita di Verona150 enrolled8 locationsNCT07498452
Recruiting
Not Applicable

Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

REM Sleep Behavior DisorderNightmareNightmare Disorder With Associated Other Sleep Disorder
University of Utah20 enrolled1 locationNCT06441864
Recruiting
Not Applicable

Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
Assistance Publique - Hôpitaux de Paris457 enrolled6 locationsNCT06582121
Recruiting
Phase 2

IMPACT 360 for Parkinson's Disease

Parkinson's Disease (PD)REM Sleep Behavior Disorder
University of British Columbia60 enrolled1 locationNCT07443293
Recruiting
Not Applicable

Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder

Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
University of Zurich80 enrolled1 locationNCT07355842
Recruiting
Not Applicable

Development and Online Evaluation of an Online Course for Parasomnias

REM Sleep Behavior Disorder (iRBD)Sleep TerrorSleepwalking+2 more
University of Manitoba20 enrolled1 locationNCT07361315
Recruiting

Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR

Parkinson DiseaseNeurodegenerative DiseasesREM Sleep Behavior Disorder (iRBD)
University of Exeter30 enrolled1 locationNCT05205291
Recruiting
Not Applicable

Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder

Parkinson DiseaseDementia With Lewy BodiesREM Sleep Behavior Disorder
University of Minnesota60 enrolled1 locationNCT06467461
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915
Recruiting
Not Applicable

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+8 more
Radboud University Medical Center110 enrolled1 locationNCT06193252
Recruiting
Not Applicable

Neuroplasticity in RBD

REM Sleep Behavior Disorder
University of Minnesota86 enrolled1 locationNCT05471960
Recruiting

Intestinal Immunity in Neurologic Disease

Multiple SclerosisParkinson DiseaseREM Sleep Behavior Disorder
Yale University100 enrolled1 locationNCT06329453
Recruiting
Not Applicable

The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders

NarcolepsyREM Sleep Behavior DisorderInsomnia Chronic
Second Affiliated Hospital of Soochow University20 enrolled1 locationNCT06797284
Recruiting
Not Applicable

Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder

Parkinson DiseaseREM Sleep Behavior DisorderDementia, Lewy Body
Insel Gruppe AG, University Hospital Bern20 enrolled1 locationNCT06629207
Recruiting

North American Prodromal Synucleinopathy Consortium Stage 2

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+3 more
Washington University School of Medicine500 enrolled9 locationsNCT05826457
Recruiting

The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls

Concussion, BrainREM Sleep Behavior Disorder
Guy's and St Thomas' NHS Foundation Trust140 enrolled1 locationNCT06270290
Recruiting

Gut Microbiota in the Progression of Alpha-synucleinopathies

REM Sleep Behavior Disorder
Chinese University of Hong Kong490 enrolled1 locationNCT05353868