Cortisol Clinical Trials

27 recruitingLast updated: June 18, 2026

There are 27 actively recruiting cortisol clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Phase 4. Top locations include Chongqing, Chongqing Municipality, China, Rochester, Minnesota, United States, Bergen, Norway. Updated daily from ClinicalTrials.gov.


Cortisol Trials at a Glance

27 actively recruiting trials for cortisol are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Chongqing, Rochester, and Bergen. Lead sponsors running cortisol studies include Qifu Li, Mayo Clinic, and Haukeland University Hospital.

Browse cortisol trials by phase

Treatments under study

About Cortisol Clinical Trials

Looking for clinical trials for Cortisol? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cortisol trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cortisol clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Phase 2

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 DiabetesCortisol Excess
Sparrow Pharmaceuticals1,500 enrolled60 locationsNCT07296484
Recruiting

Diagnostic Value of 68Ga-Pentixafor PET/CT in Adrenal Tumors With Aldosterone and Cortisol Cosecretion

Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
Peking University First Hospital130 enrolled1 locationNCT07605156
Recruiting
Not Applicable

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Primary AldosteronismHypercortisolismAldosterone-Producing Adenoma
Haukeland University Hospital60 enrolled1 locationNCT05368090
Recruiting

Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion

Primary AldosteronismAdrenal InsufficiencyAutonomous Cortisol Secretion
Qifu Li521 enrolled1 locationNCT06955286
Recruiting
Not Applicable

Ultradian Steroid Rhythms in Adrenal Incidentalomas

Mild Autonomous Cortisol Secretion AdenomaNon Secreting Adenoma
University Hospital, Bordeaux40 enrolled1 locationNCT07387419
Recruiting
Not Applicable

IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion

Mild Autonomous Cortisol Secretion (MACS)Autonomous Cortisol Secretion (ACS)Subclinical Cushing's+1 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT07361874
Recruiting
Phase 4

Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)

Mild Autonomous Cortisol Secretion (MACS)
Johns Hopkins University10 enrolled1 locationNCT07247058
Recruiting
Not Applicable

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

NeoplasiaOsteoporosisObesity, Overweight+6 more
Meyer Children's Hospital IRCCS100 enrolled1 locationNCT07412782
Recruiting
Phase 2

Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)

Mild Autonomous Cortisol SecretionAutonomous Cortisol Secretion (ACS)
Mayo Clinic15 enrolled1 locationNCT07104812
Recruiting
Not Applicable

68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Diagnosing Unilateral Subtype of Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion (PREDICT)

Primary AldosteronismAutonomous Cortisol Secretion
Qifu Li178 enrolled1 locationNCT06833437
Recruiting
Not Applicable

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

DepressionMindfulnessAnxiety+8 more
Mayo Clinic40 enrolled1 locationNCT07351799
Recruiting

Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma

Mild Autonomous Cortisol Secretion (MACS)
The Cleveland Clinic20 enrolled1 locationNCT06344143
Recruiting
Not Applicable

Effects of PeptiSleep on Sleep Quality in Healthy Adults

Wearable TechnologySleepHealthy Participants+2 more
Nuritas Ltd120 enrolled1 locationNCT07258433
Recruiting
Not Applicable

Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.

Sleep QualityDepressionStress+14 more
Leeds Beckett University40 enrolled1 locationNCT07319117
Recruiting
Phase 2

Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism

HypercortisolismHyperaldosteronismCushing s Syndrome
National Cancer Institute (NCI)80 enrolled1 locationNCT06246357
Recruiting
Phase 4

Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)

Mild Autonomous Cortisol Secretion (MACS)
Laikο General Hospital, Athens150 enrolled1 locationNCT07268222
Recruiting
Not Applicable

Light in Healthcare Environment (Ljus i sjukhusmiljö)

Sleep QualityWell-beingCortisol+2 more
Lund University18 enrolled3 locationsNCT06687304
Recruiting

Salivary Cortisol and Hypercortisolism in Type 2 Diabetes

Type 2 Diabetes (T2DM)Hypercortisolism
Shanghai 6th People's Hospital500 enrolled1 locationNCT07156370
Recruiting
Not Applicable

Early Psychological Intervention After Rape

Activity, MotorDepression, AnxietySleep Disturbance+6 more
St. Olavs Hospital200 enrolled4 locationsNCT05489133
Recruiting

A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

Adrenal InsufficiencyHypercortisolismEndogenous Cushing Syndrome
University of Michigan12 enrolled1 locationNCT06430528