Phase 3 Head and Neck Cancer Clinical Trials

13 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 113 of 13 trials

Recruiting
Phase 2Phase 3

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE350 enrolled193 locationsNCT04534205
Recruiting
Phase 3

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Cancer
Canadian Cancer Trials Group196 enrolled6 locationsNCT06641791
Recruiting
Phase 2Phase 3

A Trial Evaluating Omission of Radiotherapy to Regional Lymphatic's

Head and Neck Cancer
All India Institute of Medical Sciences396 enrolled1 locationNCT07528495
Recruiting
Phase 3

Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for Head and Neck Cancer Patients Undergoing Radiation Therapy

Head and Neck Cancer
West China Hospital170 enrolled1 locationNCT07467083
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Head and Neck CancerTaste Dysfunction
University of California, San Francisco40 enrolled1 locationNCT05273307
Recruiting
Phase 3

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Head and Neck CancerRenal Cell CarcinomaLung Cancer Metastatic
UNICANCER646 enrolled40 locationsNCT05078047
Recruiting
Phase 3

Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer

Head and Neck CancerOropharynx CancerHuman Papilloma Virus
Centre hospitalier de l'Université de Montréal (CHUM)360 enrolled2 locationsNCT04178174
Recruiting
Phase 2Phase 3

Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors

Breast CancerOvarian CancerCervical Cancer+7 more
Second Affiliated Hospital of Guangzhou Medical University200 enrolled1 locationNCT03755739
Recruiting
Phase 3

Optimising Patient Experience in Head and Neck Radiotherapy

Head and Neck Cancer
Irish Research Radiation Oncology Group201 enrolled1 locationNCT06327139
Recruiting
Phase 3

Efficacy and safety of local anesthesia in patients with head and neck tumors undergoing percutaneous endoscopic gastrostomy (PEG): Lidocaine versus ropivacaine - Prospective, randomized, double blind study

Percutaneous endoscopic gastrostomy (PEG)CancerHead and Neck cancer patients
Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE30 enrolled1 locationACTRN12618000713291
Terminated
Phase 2Phase 3

Does Mepitel Film decrease skin reactions caused by radiation therapy in head and neck cancer patients?

Acute radiation-induced skin reactionsHead and Neck Cancer
Otago University86 enrolled2 locationsACTRN12616000725460
Terminated
Phase 3

Hyperbaric Oxygen Therapy for Radiation Induced Xerostomia (Dry Mouth)

Soft tissue radiation injury to salivary glands (xerostomia)Head and Neck Cancer
Dr S Sherlock60 enrolled1 locationACTRN12612000084886