Liver Disease Clinical Trials

6 recruiting

Liver Disease Trials at a Glance

246 actively recruiting trials for liver disease are listed on ClinicalTrialsFinder across 6 cities in 51 countries. The largest study group is Not Applicable with 84 trials, with the heaviest enrollment activity in New York, Indianapolis, and Los Angeles. Lead sponsors running liver disease studies include Assistance Publique - Hôpitaux de Paris, Chinese University of Hong Kong, and Hospices Civils de Lyon.

Browse liver disease trials by phase

Treatments under study

About Liver Disease Clinical Trials

Looking for clinical trials for Liver Disease? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 246 trials

Recruiting

Evaluation of Patients With Liver Disease

Hepatitis BHepatitis CLiver Disease+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)8,050 enrolled1 locationNCT00001971
Recruiting
Phase 2

Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting

Liver Steatosis in Pediatric CD Patients

Non-Alcoholic Fatty Liver DiseaseCeliac Disease in Children
University of Palermo91 enrolled2 locationsNCT06206616
Recruiting
Phase 1

Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy Drinkers

Alcohol Associated Liver DiseaseHeavy Drinking Behavior
National Institute on Alcohol Abuse and Alcoholism (NIAAA)100 enrolled1 locationNCT04781322
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)

Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

Non-Alcoholic Fatty Liver DiseaseLow Birth Weight
Steno Diabetes Center Copenhagen300 enrolled1 locationNCT05890365
Recruiting

Impact of Iron Overload on the Incidence of Liver Complications in Long-Term Survivors (≥10 Years) of Allogeneic Hematopoietic Stem-Cell Transplantation.

Liver DiseasesHematopoietic Stem Cell Transplantation (HSCT)Iron Overload+1 more
Assistance Publique - Hôpitaux de Paris500 enrolled1 locationNCT07028112
Recruiting
Not Applicable

Rehabilitation With Exercise-Based Intervention for Nonalcoholic Chronic Hepatic Esteatosis

Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD)Metabolic Adaptation to High-Intensity Interval Training
Universidad San Sebastián30 enrolled1 locationNCT07552727
Recruiting
Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company4,500 enrolled561 locationsNCT07165028
Recruiting
Not Applicable

Assessing Declined Liver Grafts With Normothermic Machine Perfusion to Reduce Transplant Waiting Time

SurgeryLiver DiseasesLiver Transplantation
Charite University, Berlin, Germany186 enrolled10 locationsNCT06874296
Recruiting

Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

Liver NeoplasmLiver FibrosisHBV Infection+1 more
Nanfang Hospital, Southern Medical University240 enrolled1 locationNCT07265544
Recruiting

CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome

Non-Alcoholic Fatty Liver Disease
Institut National de la Santé Et de la Recherche Médicale, France710 enrolled1 locationNCT05623150
Recruiting
Not Applicable

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

Alcohol Use DisorderAlcohol-related Liver Disease
University of Wisconsin, Madison298 enrolled3 locationsNCT06305624
Recruiting
Not Applicable

Time-restricted Feeding in MASLD

Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD)
Universität des Saarlandes120 enrolled1 locationNCT07530809
Recruiting
Not Applicable

Online Prehabilitation for Patients Awaiting Liver Transplantation

Liver Transplant SurgeryCirrhosis, LiverLiver Disease
University of Alberta177 enrolled6 locationsNCT05899231
Recruiting
Phase 1

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin ResistanceNon-Alcoholic Fatty Liver DiseaseOverweight and Obesity+1 more
Columbia University32 enrolled1 locationNCT06354088
Recruiting
Phase 1

Effect of Insulin Lowering on Lipogenesis

ObesityInsulin ResistanceNon-Alcoholic Fatty Liver Disease+2 more
Columbia University25 enrolled1 locationNCT07403604
Recruiting

DILIN - Prospective Study

Liver Diseases
Duke University4,000 enrolled6 locationsNCT00345930
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

Liver Diseases, Alcoholic
GlaxoSmithKline393 enrolled131 locationsNCT06613698