Refractory Epilepsy Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Refractory Epilepsy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables

Focal EpilepsyGeneralized SeizureDrug Refractory Epilepsy
Mayo Clinic12 enrolled1 locationNCT07012148
Recruiting
Not Applicable

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application

Refractory EpilepsyEpilepsyMusic
Dartmouth-Hitchcock Medical Center24 enrolled2 locationsNCT06425029
Recruiting
Early Phase 1

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Refractory EpilepsyDeep Brain Stimulation
University of Minnesota20 enrolled1 locationNCT05493722
Recruiting
Not Applicable

Model-based Electrical Brain Stimulation

Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring
University of Southern California25 enrolled2 locationsNCT05327387
Recruiting
Not Applicable

Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy

Refractory Epilepsy
Cliniques universitaires Saint-Luc- Université Catholique de Louvain34 enrolled1 locationNCT06304389
Recruiting
Not Applicable

Focused Ultrasound for Drug-resistant Epilepsy

Drug Resistant EpilepsyDrug Refractory EpilepsyFocused Ultrasound+2 more
Taipei Veterans General Hospital, Taiwan20 enrolled1 locationNCT06292494
Recruiting

Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy

Refractory Epilepsy in Children
Guangzhou Women and Children's Medical Center100 enrolled1 locationNCT07064421
Recruiting
Not Applicable

Investigating the Functional Characteristics During Wakefulness and Sleep Based on SEEG

Refractory EpilepsySleep
Xuanwu Hospital, Beijing20 enrolled1 locationNCT06524479
Recruiting
Not Applicable

Optimal Stimulation Parameters to Disrupt Epileptiform Activity

Refractory Epilepsy
Massachusetts General Hospital30 enrolled1 locationNCT06141668
Recruiting
Not Applicable

Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy

Refractory EpilepsyEpilepsySeizures+4 more
Neuroelectrics Corporation190 enrolled32 locationsNCT04770337
Recruiting

Atlas of Human Cognition by SEEG (MAPCOG-SEEG)

Refractory EpilepsyFocal Epilepsy
University Hospital, Grenoble200 enrolled4 locationsNCT03644732
Recruiting
Not Applicable

High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy

Refractory EpilepsyTranscranial Direct Current StimulationFunctional Magnetic Resonance Imaging+2 more
Anhui Medical University90 enrolled1 locationNCT06241963