Progressive Aphasia Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Progressive Aphasia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting

Speech and Language Interventions for Italian People With PPA

Primary Progressive Aphasia(PPA)
Istituti Clinici Scientifici Maugeri SpA30 enrolled2 locationsNCT06739967
Recruiting
Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

Corticobasal Syndrome(CBS)Progressive Supranuclear Palsy (PSP)Primary Progressive Aphasia(PPA)+6 more
University of Pennsylvania1,000 enrolled1 locationNCT04715399
Recruiting
Not Applicable

Remotely-supervised Neuromodulation in PPA

Primary Progressive Aphasia(PPA)Progressive AphasiaProgressive Aphasia in Alzheimer's Disease+3 more
University of Texas at Austin80 enrolled2 locationsNCT07260253
Recruiting

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

DementiaAlzheimer DiseaseParkinson Disease+7 more
University Health Network, Toronto500 enrolled4 locationsNCT06529744
Recruiting
Not Applicable

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

DementiaAlzheimer DiseaseCommunication Disorders+11 more
University of Texas at Austin60 enrolled3 locationsNCT05741853
Recruiting
Not Applicable

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Alzheimer Disease, Early OnsetAtypical Alzheimer's DiseaseLogopenic Progressive Aphasia
Johns Hopkins University90 enrolled1 locationNCT04122001
Recruiting
Not Applicable

Long Term Effect of Brain Stimulation in PPA

Primary Progressive Aphasia(PPA)
Hospital San Carlos, Madrid80 enrolled1 locationNCT07158216
Recruiting
Phase 2

Communication Bridge 3 Study

Primary Progressive Aphasia
University of Chicago200 enrolled1 locationNCT06191198
Recruiting
Early Phase 1

Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia

DementiaAlzheimer DiseaseProgressive Aphasia+3 more
University of Texas at Austin120 enrolled1 locationNCT06511752
Recruiting
Not Applicable

A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931

Primary Progressive Aphasia
IRCCS Centro San Giovanni di Dio Fatebenefratelli60 enrolled4 locationsNCT05730023